143343-85-5Relevant articles and documents
PRODUCTION OF DOLASETRON
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Page/Page column 51-52, (2008/06/13)
The present invention provides an improved process for the preparation of Dolasetron salts, in particularly Dolasetron mesylate. % Also provided are intermediates for the process and methods of preparing the intermediates.
Process for preparing indole-3-carboxylic acid esters of trans-hexahydro-8-hydroxy-2,6-methano-2H-quinolizin-3(4H)-one
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, (2008/06/13)
The present invention describes a process for preparing indole-3-carboxylic acid esters of hexahydro-8-hydroxy-2,6--methano-2H-quinolizin-3(4H)-one which comprises reacting 5--hydroxy-8-azatricyclo[5. 3.1.03,8]undecan-10-one with the mixed anhydride of trifluoroacetic acid and an appropriate indole-3-carboxylic acid.