143358-20-7

Upstream product

• 13057-72-2 7-hydroxyisoflavone 
• 97714-85-7 7-ethoxymethoxyisoflavanone 
• 97714-82-4 2-hydroxy-4-ethoxymethoxyphenyl α-hydroxymethylbenzyl ketone 
• 3669-41-8 1-(2,4-dihydroxyphenyl)-2-phenylethanone 
• 68-12-2 N,N-dimethyl-formamide 
• 103-82-2 phenylacetic acid 
• 108-46-3 recorcinol 
• 97714-79-9 benzyl 4-ethoxymethoxy-2-hydroxyphenyl ketone 
• 65490-06-4 1-(2-Hydroxy-4-methoxymethoxy-phenyl)-2-phenyl-ethanone 
• 342643-51-0 isoflavanone 

Downstream Products

• 5128-69-8 7-methoxyisoflavanone 
• 7734-88-5 7-acetoxy-3-phenyl-chroman-4-one 
• 105705-46-2 7-hydroxy-8-C-prenylisoflavanone 

Relevant academic research and scientific papers

INHIBITORS OF ANTIGEN PRESENTATION BY HLA-DR

Chromanone compounds, pharmaceutical compositions containing them, methods of making them, and methods of using them including methods for treating disease states, disorders, and conditions associated with the inhibition of antigen presentation by HLA-DR.

Enantioselective Synthesis of Isoflavanones by Catalytic Dynamic Kinetic Resolution

A ruthenium-catalyzed asymmetric transfer hydrogenation of racemic isoflavanones with dynamic kinetic resolution yields virtually enantiopure isoflavanols as single diastereomers. Subsequent oxidation gives rise to isoflavanones in high enantiomeric purit

Development of 3-alkyl-6-methoxy-7-hydroxy-chromones (AMHCs) from natural isoflavones, a new class of fluorescent scaffolds for biological imaging

Starting from 7-hydroxyisoflavones, we developed a new class of fluorescent scaffolds, 3-alkyl-6-methoxy-7-hydroxy-chromones (AMHCs, MW ～ 205.19, λab ～ 350 nm, λem ～ 450 nm) via a trial and error process. AMHCs have the advantages of being a small molecular moiety, having strong fluorescence in basic buffers, reasonable solubility and stability, non-toxicity, and are conveniently linked to pharmacophores. AMHCs were successfully used in fluorescence microscopy imaging of cells and tissues. This journal is

Formation of hydridocobalt(iii) phthalocyanine by reaction of cobalt(ii) phthalocyanines with sodium borohydride and its reactions with antioxidant isoflavones

The reduction of substituted isoflavones with sodium borohydride catalyzed by cobalt(ii) phthalocyanines has been achieved efficiently to yield cis- and trans-isoflavan-4-ols under mild conditions via the formation of a hydridocobalt(iii) phthalocyanine i

A simple synthesis of hydroxyisoflavanones

The isoflavanoids 7-hydroxyisoflavanone 4a, 7-hydroxy-3′, 4′-dimethoxyisoflavanone 4b, 5, 7-dihydroxy-3′, 4′-dimethoxyisoflavanone 4c, 5, 7-dihydroxy-2′-methoxyisoflavanone 4d, 5, 7-dihydroxy-3′, 4′-dimethoxyisoflavanone 4e and 5, 7-dihydroxy-4′-methoxyisoflavanone 4f have been conveniently prepared by using paraforomaldehyde and diethylamine as a base.

HYDROGEN TRANSFER REDUCTION OF ISOFLAVONES

Hydrogen transfer reduction of isoflavones using ammonium formate and palladium charcoal provides an easy access to polyoxyisoflavanones and also to isoflavan-4-ols without the need for protection of the hydroxy groups.Optimized reaction conditions for im

A New General Synthesis of Hydroxy- and Methoxy-isoflavones

A new general synthesis of hydroxy- (5e-h) and methoxy- (5e-d) isoflavones has been accomplished in overall yields of 47-73percent from the corresponding 2-hydroxydeoxybenzoins (1a-h).The first step involves reaction with appropriate amounts of ethoxymeth

CATALYTIC TRANSFER HYDROGENATION, A CHEMO-SELECTIVE REDUCTION OF ISOFLAVONES TO ISOFLAVANONES

Isoflavones can be selectively reduced by catalytic transfer hydrogenation employing formic acid, ammonium formate or triethylammonium formate in the presence of 10percent Pd/C.The reaction is simple, clean and gives fair yields of isoflavanones.

A New General Synthesis of Polyhydroxyisoflavanones

Hydroxyisoflavanones have been conveniently synthesised from hydroxydesoxybenzoins in 47-57 percent overall yields in four steps which could be carried out either continuously or by isolating the products at each stage.