1433688-86-8

Basic information

• Product Name: 3-(5-Bromopyrimidin-4-yl)-1-ethyl-1H-indole
• Synonyms: 3-(5-Bromopyrimidin-4-yl)-1-ethyl-1H-indole
• CAS NO: 1433688-86-8
• Molecular Weight: 302.173
• Mol File: 1433688-86-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(5-Bromopyrimidin-4-yl)-1-ethyl-1H-indole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(5-Bromopyrimidin-4-yl)-1-ethyl-1H-indole(1433688-86-8)
• EPA Substance Registry System: 3-(5-Bromopyrimidin-4-yl)-1-ethyl-1H-indole(1433688-86-8)

Safety Data

• Hazardous Substances Data: 1433688-86-8(Hazardous Substances Data)

Downstream Products

• 1433688-91-5 1-ethyl-3-(pyrimidin-4-yl)-1H-indole 
• 1433689-03-2 1-ethyl-3-[5-(3-nitrophenyl)pyrimidin-4-yl]-1H-indole 

Relevant articles and documents

Consecutive SNH and Suzuki-Miyaura cross-coupling reactions-an efficient synthetic strategy to pyrimidines bearing pyrrole and indole fragments

The combination of the Suzuki-Miyaura cross-coupling and nucleophilic aromatic substitution of hydrogen reactions is a versatile tool for the syntheses of 4-(1R-pyrrol-2-yl)-and 4-(1R-indol-3-yl)-5-(hetero)aryl-substituted pyrimidines from commercially available 5-bromopyrimidine. The S NH [AE, (addition-elimination)] and SN H [AO, (addition-oxidation)] reactions of 5-bromopyrimidine with pyrroles and indoles were studied by gas chromatography-mass spectrometry. The structures of the intermediate σH adducts as well as the pyrrole-(hetero)arylpyrimidine and indole-(hetero)arylpyrimidine dyads were established for the first time by X-ray crystal structure analysis.