143370-20-1

Basic information

• Product Name: 6-(2-acetyl-4-methoxy-phenylamino)quinoline-5,8-dione
• Synonyms: 6-(2-acetyl-4-methoxy-phenylamino)quinoline-5,8-dione
• CAS NO: 143370-20-1
• Molecular Weight: 322.32
• Mol File: 143370-20-1.mol

Chemical Properties

• CAS DataBase Reference: 6-(2-acetyl-4-methoxy-phenylamino)quinoline-5,8-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(2-acetyl-4-methoxy-phenylamino)quinoline-5,8-dione(143370-20-1)
• EPA Substance Registry System: 6-(2-acetyl-4-methoxy-phenylamino)quinoline-5,8-dione(143370-20-1)

Safety Data

• Hazardous Substances Data: 143370-20-1(Hazardous Substances Data)

Upstream product

• 10470-83-4 5,8-quinolinedione 
• 23042-77-5 1-(2-amino-5-methoxy-phenyl)-ethanone 
• 54232-20-1 6-methoxy-5,8-quinolinedione 

Downstream Products

• 143370-23-4 neocalliactine methyl ether 
• 143370-23-4 5-methoxyascididemin 

Relevant articles and documents

TOTAL SYNTHESIS OF KUANONIAMINE A, 11-HYDROXYASCIDIDEMIN, AND NEOCALLIACTINE ACETATE

A pentacyclic aromatic alkaloid, kuanoniamine A (5) was synthesized from 6-methoxybenzothiazole-4,7-dione (7) and 2-aminoacetophenone (8).Similarly, 11-hydroxyascididemin (4) was prepared from 6-bromo-4-chloro-5,8-dimethoxyquinoline (12).The structure of neocalliactine acetate, a derivative of calliactine, was determined as 19 by total synthesis from 6-methoxy-5,8-quinolinedione (23) and 2-amino-5-methoxyacetophenone (24).

Synthesis and in vitro antitumor activity of novel ring D analogues of the marine pyridoacridine ascididemin: Structure-activity relationship

Marine compounds with pyridoacridine skeletons are known to exhibit interesting antitumor activities. Ascididemin has already been reported as displaying significant antitumor activities in vitro and has also been found to have a relatively high global to

Synthetic studies on pentacyclic aromatic alkaloids, kuanoniamine A, 11-hydroxyascididemin, and neocalliactine acetate

A pentacyclic aromatic alkaloid, kuanoniamine A (6) was synthesized in three steps from 6-methoxybenzothiazole-4,7-dione (8) and 2-aminoacetophenone (9). 11-Hydroxyascididemin (4) was prepared from 5,8-quinolinedione (13, 14) or 1,4-acridinedione (20). The structure of neocalliactine acetate, a derivative of calliactine, was determined to be 5 by total synthesis from 6-methoxy-5,8-quinolinedione (28) and 2-amino-5-methoxyacetophenone (29).

Polycyclic Aromatic Alkaloids, 8. The Structure of Neocalliactine Acetate - Proof by Total Synthesis

The pentacyclic compound 1 is prepared in six steps by starting from 5,8-quinolinedione (7).Its spectral data are in accordance with those of neocalliactine acetate, a derivative of the marine alkaloid calliactine.This represents the first definite confir