143382-88-1 Usage
General Description
The chemical "1-cyclopropyl-7-{(3R)-3-[(1S)-1-(ethylamino)ethyl]pyrrolidin-1-yl}-6-fluoro-4-oxo-8-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxylic acid" is a quinolone antibiotic used to treat bacterial infections. It belongs to the fluoroquinolone class of antibiotics and works by inhibiting bacterial DNA replication and transcription, leading to the death of the bacteria. The presence of the cyclopropyl, fluoro, and trifluoromethyl groups in the chemical structure enhance its antimicrobial activity and increase its spectrum of activity against a wide range of bacteria. This chemical is typically administered orally and has demonstrated efficacy against both Gram-positive and Gram-negative bacteria, making it a valuable treatment option for various infections.
Check Digit Verification of cas no
The CAS Registry Mumber 143382-88-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,3,3,8 and 2 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 143382-88:
(8*1)+(7*4)+(6*3)+(5*3)+(4*8)+(3*2)+(2*8)+(1*8)=131
131 % 10 = 1
So 143382-88-1 is a valid CAS Registry Number.
143382-88-1Relevant articles and documents
Quinolone Antibacterials Containing the New 7- Side Chain: The Effects of the 1-Aminoethyl Moiety and Its Stereochemical Configurations on Potency and in Vivo Efficacy
Domagala, John M.,Hagen, Susan E.,Joannides, Themis,Kiely, John S.,Laborde, Edgardo,et al.
, p. 871 - 882 (2007/10/02)
A series of stereochemically pure 7--1,4-dihydro-4-oxoquinoline and 1,8-naphthyridine-3-carboxylic acids, with varied substituents at the 1-, 5-, and 8-positions, were synthesized to study the effects of the 7-3-(1-aminoe