1433890-57-3

Upstream product

• 1433890-51-7 (S)-3-amino-1-(1-(3-isopropyl-1,2,4-thiadiazol-5-yl)piperidin-4-yl)pyrrolidin-2-one 
• 32779-36-5 5-Bromo-2-chloropyrimidine 
• 1433890-44-8 (S)-tert-butyl 1-(1-(3-isopropyl-1,2,4-thiadiazol-5-yl)piperidin-4-yl)-2-oxopyrrolidin-3-ylcarbamate 
• 1433890-38-0 (S)-(3-(tert-butoxycarbonylamino)-4-(1-(3-isopropyl-1,2,4-thiadiazol-5-yl)piperidin-4-ylamino)-4-oxobutyl)dimethylsulfonium iodide 
• 1433890-31-3 (S)-tert-butyl 1-(1-(3-isopropyl-1,2,4-thiadiazol-5-yl)piperidin-4-ylamino)-4-(methylthio)-1-oxobutan-2-ylcarbamate 

Relevant academic research and scientific papers

PIPERIDINYL-SUBSTITUTED LACTAMS AS GPR119 MODULATORS

Compounds of Formula (I) and pharmaceutically acceptable salts thereof in which X1, X2, X3, L, R3, R4, R5, R7 and n have the meanings given in the specification, are modulators of GPR119 and are useful in the treatment or prevention of diseases such as such as, but not limited to, type 2 diabetes, diabetic complications, symptoms of diabetes, metabolic syndrome, obesity, dyslipidemia, and related conditions.