143395-98-6

Basic information

• Product Name: (1S,2R,3S,4R)-4-[7-[1(R)-(3-Chloro-2-thienylmethyl)propylamino]-3H-imidazo[4,5-b]pyridin-3-yl]-N-ethyl-2,3-dihydroxycyclopentane-1-carboxamide
• Synonyms: RPR-100579; AMP-579
• CAS NO: 143395-98-6
• Molecular Formula: C₂₂H₂₈ClN₅O₃S
• Molecular Weight: 478.01716
• Mol File: 143395-98-6.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: (1S,2R,3S,4R)-4-[7-[1(R)-(3-Chloro-2-thienylmethyl)propylamino]-3H-imidazo[4,5-b]pyridin-3-yl]-N-ethyl-2,3-dihydroxycyclopentane-1-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,2R,3S,4R)-4-[7-[1(R)-(3-Chloro-2-thienylmethyl)propylamino]-3H-imidazo[4,5-b]pyridin-3-yl]-N-ethyl-2,3-dihydroxycyclopentane-1-carboxamide(143395-98-6)
• EPA Substance Registry System: (1S,2R,3S,4R)-4-[7-[1(R)-(3-Chloro-2-thienylmethyl)propylamino]-3H-imidazo[4,5-b]pyridin-3-yl]-N-ethyl-2,3-dihydroxycyclopentane-1-carboxamide(143395-98-6)

Safety Data

• Hazardous Substances Data: 143395-98-6(Hazardous Substances Data)

Usage

Description

(1S,2R,3S,4R)-4-[7-[1(R)-(3-Chloro-2-thienylmethyl)propylamino]-3H-imidazo[4,5-b]pyridin-3-yl]-N-ethyl-2,3-dihydroxycyclopentane-1-carboxamide is a complex organic molecule with a cyclopentane-1-carboxamide core. It features a 3H-imidazo[4,5-b]pyridin-3-yl group, an N-ethyl group, a 3-chloro-2-thienylmethyl substituent, and a propylamino side chain attached to the imidazo[4,5-b]pyridin-3-yl group. The presence of multiple hydroxyl groups suggests potential pharmaceutical applications, although further research is required to determine its specific biological activity.

Uses

Used in Pharmaceutical Industry:
(1S,2R,3S,4R)-4-[7-[1(R)-(3-Chloro-2-thienylmethyl)propylamino]-3H-imidazo[4,5-b]pyridin-3-yl]-N-ethyl-2,3-dihydroxycyclopentane-1-carboxamide is used as a potential pharmaceutical compound for its complex structure and multiple functional groups, which may contribute to its biological activity and therapeutic potential. Further research is needed to explore its specific applications and efficacy in treating various medical conditions.

Upstream product

• 1634-04-4 tert-butyl methyl ether 
• 100-68-5 methyl-phenyl-thioether 
• 280756-72-1 [3aR-[3aα,4α,6a(R*),6aα]]-6-[4-[[1-[(3-chlorothien-2-yl)methyl]propyl][4-methylbenzenesulfonyl]amino]-3-nitropyrid-2-ylamino] N-ethyl tetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxole-4-carboxamide 
• 280756-73-2 [3aR-[3aα,4α,6a(R*),6aα]]-6-[4-[[1-[(3-chlorothien-2-yl)methyl]propyl][4-methylbenzenesulfonyl]amino]-3-aminopyrid-2-ylamino] N-ethyl tetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxole-4-carboxamide 
• 313268-73-4 [3aR-[3aα,4α,6a(R*),6aα]]-6-[7-[[1-[(3-chlorothien-2-yl)methyl]propyl][4-methylbenzenesulfonyl]amino]-3H-imidazo(4,5-b)pyrid-3-yl] N-ethyl tetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxole-4-carboxamide 
• 280756-71-0 (R)-N-[1-[(3-chlorothien-2-yl)methyl]propyl]-N-(2-fluoro-3-nitropyrid-4-yl)-4-methylbenzenesulfonamide 
• 60186-14-3 2,4-difluoro-3-nitropyridine 
• 5975-12-2 2,4-dichloro-3-nitro-pyridine 
• 313268-74-5 [3aR-[3aα,4α,6a(R*),6aα]]-6-[7-[[1-[(3-chlorothien-2-yl)methyl]propyl]amino]-3H-imidazo(4,5-b)pyrid-3-yl] N-ethyl tetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxole-4-carboxamide 

Relevant articles and documents

Process for preparing N6-substituted adenosine derivatives

This invention is directed to a process for preparing N6-substituted adenosine derivatives, to intermediates useful therefor and to methods of preparing these intermediates.

Efficient synthesis of AMP579, a novel Adenosine A1/A2 receptor agonist

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COMPOUNDS HAVING ANTIHYPERTENSIVE, CARDIOPROTECTIVE, ANTI-ISCHEMIC AND ANTILIPOLYTIC PROPERTIES

Compounds of the Formula STR1 wherein: K is N or N→O; Q is CH. sub.2 or O; T is STR2 or R 3 O--CH 2 ; X is a straight or branched chain alkylene, cycloalkylene or cycloalkenylene group, each of which is optionally substituted by at least one CH 3, CH 3 CH