1433962-91-4Relevant academic research and scientific papers
Organocatalytic asymmetric Michael addition of ethyl nitroacetate to enones using natural amino acids-derived C1-symmetric chiral primary-secondary diamines
Zhou, Yirong,Liu, Qiang,Gong, Yuefa
supporting information, p. 3011 - 3014 (2013/06/26)
A highly organocatalytic asymmetric Michael addition of ethyl nitroacetate to enones by using C1-symmetric chiral primary-secondary diamines has been developed. In assistance of o-nitrobenzoic acid, chiral amine 1f which was derived from l-tryptophane and d-camphor can effectively promote the transformation in high yields (up to 96%) and enantioselectivities (up to 95%) under mild conditions.
