FMoc-D-4-Aph(tBu-CbM)-OH is a chemical compound that consists of a 9-fluorenylmethoxycarbonyl (FMoc) protected D-4-amino phenylalanine (4-Aph) with tert-butyl (tBu) and carboxybenzyl (CbM) protection group at the amino and carboxyl terminus. It is a versatile building block in peptide synthesis, known for its stability and compatibility with solid-phase peptide synthesis techniques, making it a valuable tool for the creation of diverse peptide structures.
1433975-21-3
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Basic information
- Product Name: FMoc-D-4-Aph(tBu-CbM)-OH
- Synonyms: FMoc-D-4-Aph(tBu-CbM)-OH;4-[[[(1,1-Dimethylethyl)amino]carbonyl]amino]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-phenylalanine;(9H-Fluoren-9-yl)MethOxy]Carbonyl D-Aph(tBuCbm)-OH
- CAS NO:1433975-21-3
- Molecular Formula: C29H31N3O5
- Molecular Weight: 501.57354
- EINECS: -0
- Product Categories: N/A
- Mol File: 1433975-21-3.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: 2-8°C
- Solubility: N/A
- CAS DataBase Reference: FMoc-D-4-Aph(tBu-CbM)-OH(CAS DataBase Reference)
- NIST Chemistry Reference: FMoc-D-4-Aph(tBu-CbM)-OH(1433975-21-3)
- EPA Substance Registry System: FMoc-D-4-Aph(tBu-CbM)-OH(1433975-21-3)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 1433975-21-3(Hazardous Substances Data)
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1433975-21-3 Usage
Uses
Used in Pharmaceutical Research:FMoc-D-4-Aph(tBu-CbM)-OH is used as a building block in peptide synthesis for the development of novel pharmaceutical compounds. Its incorporation into peptides allows for the modification of peptide properties, enabling the exploration of new therapeutic agents with improved efficacy and selectivity.
Used in Biochemical Studies:
In biochemical research, FMoc-D-4-Aph(tBu-CbM)-OH serves as a key component in the synthesis of peptides with specific functionalities. Its use facilitates the study of peptide-protein interactions, enzyme substrate specificity, and the development of bioactive peptides with potential applications in various biological processes.
Used in Drug Development:
FMoc-D-4-Aph(tBu-CbM)-OH is utilized in the design and synthesis of peptide-based drugs, offering a means to introduce the 4-Aph residue into peptide sequences. This modification can enhance the pharmacokinetic and pharmacodynamic properties of peptide drugs, leading to the development of more effective and targeted therapeutics.
Used in Peptide Synthesis Industry:
FMoc-D-4-Aph(tBu-CbM)-OH is used as a protected amino acid in the solid-phase peptide synthesis process. Its stability and compatibility with various coupling and deprotection techniques make it an essential component in the production of custom peptides and peptide-based products for research and commercial applications.
Check Digit Verification of cas no
The CAS Registry Mumber 1433975-21-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,3,3,9,7 and 5 respectively; the second part has 2 digits, 2 and 1 respectively.Calculate Digit Verification of CAS Registry Number 1433975-21:
(9*1)+(8*4)+(7*3)+(6*3)+(5*9)+(4*7)+(3*5)+(2*2)+(1*1)=173
173 % 10 = 3
So 1433975-21-3 is a valid CAS Registry Number.
1433975-21-3Upstream product
1433975-21-3Downstream Products
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FMoc-D-4-Aph(tBu-CbM)-OH
