143399-01-3

Basic information

• Product Name: (3-bromo-4-methoxy-phenyl)-acetyl chloride
• CAS NO: 143399-01-3
• Molecular Weight: 263.518
• Mol File: 143399-01-3.mol

Chemical Properties

• CAS DataBase Reference: (3-bromo-4-methoxy-phenyl)-acetyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: (3-bromo-4-methoxy-phenyl)-acetyl chloride(143399-01-3)
• EPA Substance Registry System: (3-bromo-4-methoxy-phenyl)-acetyl chloride(143399-01-3)

Safety Data

• Hazardous Substances Data: 143399-01-3(Hazardous Substances Data)

Upstream product

• 104-01-8 4-Methoxyphenylacetic acid 
• 774-81-2 (3-bromo-4-methoxy-phenyl)-acetic acid 

Downstream Products

• 29974-03-6 N-Benzyl-3-bromo-4-methoxyphenylacetamid 
• 1007893-77-7 (3-bromo-4-hydroxyphenyl)(6-bromo-9H-pyrido[3,4-b]indol-1-yl)methanone 
• 1007893-76-6 (3-bromo-4-hydroxyphenyl)(9H-pyrido[3,4-b]indol-1-yl)methanone 
• 143398-71-4 1-(3-Bromo-4-methoxy-benzyl)-6-methoxy-3-pentyl-1,2,3,4-tetrahydro-isoquinoline 
• 143398-69-0 1-(3-Bromo-4-methoxy-benzyl)-3-butyl-6-methoxy-1,2,3,4-tetrahydro-isoquinoline 
• 143398-67-8 1-(3-Bromo-4-methoxy-benzyl)-6-methoxy-3-propyl-1,2,3,4-tetrahydro-isoquinoline 
• 143398-63-4 1-(3-Bromo-4-methoxy-benzyl)-6-methoxy-3-methyl-1,2,3,4-tetrahydro-isoquinoline 
• 592529-12-9 2-(3-bromo-4-methoxy-phenyl)-1-{2-[2-(4-methylsulfanyl-phenyl)-2-oxo-ethyl]-pyrrolidin-1-yl}-ethanone 
• 29974-02-5 N-[2-(3-Benzyloxy-phenyl)-ethyl]-2-(3-bromo-4-methoxy-phenyl)-acetamide 
• 143398-61-2 2-(3-Bromo-4-methoxy-phenyl)-N-[1-(3-methoxy-benzyl)-hexyl]-acetamide 
• 143398-59-8 2-(3-Bromo-4-methoxy-phenyl)-N-[1-(3-methoxy-benzyl)-pentyl]-acetamide 
• 143398-57-6 2-(3-Bromo-4-methoxy-phenyl)-N-[1-(3-methoxy-benzyl)-butyl]-acetamide 
• 143398-56-5 2-(3-Bromo-4-methoxy-phenyl)-N-[2-(3-methoxy-phenyl)-1-methyl-ethyl]-acetamide 

Relevant articles and documents

Total syntheses of eudistomins Y1-Y7 by an efficient one-pot process of tandem benzylic oxidation and aromatization of 1-benzyl-3,4-dihydro-β-carbolines

The first total synthesis of eudistomin Y7 (7) and total syntheses of eudistomins Y1-Y6 (1-6) are described. An efficient room-temperature conversion of 1-benzyl-3,4-dihydro-β-carbolines (11) into 1-benzoyl-β-carbolines (14) by a one-pot process of tandem benzylic oxidation and aromatization as the key step of these total syntheses was also studied in detail. The first total synthesis of eudistomin Y 7 (7) and total syntheses of eudistomins Y1-Y6 (1-6) are described. An efficient room-temperature conversion of 1-benzyl-3,4-dihydro-β-carbolines (11) into 1-benzoyl-β-carbolines (14) by a one-pot process of tandem benzylic oxidation and aromatization as the key step of these total syntheses was also studied in detail. Copyright

Perylenequinone natural products: Total syntheses of the diastereomers (+)-phleichrome and (+)-calphostin D by assembly of centrochiral and axial chiral fragments

(Chemical Equation Presented) The first total synthesis of (+)-calphostin D and the total synthesis of (+)-phleichrome are outlined. The convergent syntheses utilize an enantiopure biaryl common intermediate, which is formed via an enantioselective cataly

Enantioselective synthesis of binaphthyl polymers using chiral asymmetric phenolic coupling catalysts: Oxidative coupling and tandem glaser/oxidative coupling

(Chemical Equation Presented) A series of functionalized and optically active polybinaphthyls have been synthesized from achiral substrates by asymmetric oxidative phenolic coupling using a chiral 1,5-diaza-cis-decalin copper catalyst. In most cases, a copper tetrafluoroborate catalyst was found to be superior to the copper iodide catalyst, as ortho-iodination of the substrates could be prevented. Three methods for the formation of chiral polymers are described. In the first method, two 2-naphthols linked together at C-6 are subjected to the optimized asymmetric oxidative phenolic coupling conditions to form chiral polynaphthyls. A combination of NMR and HPLC measurements secured the selectivity of the asymmetric coupling. In the second method, substrates containing only one naphthalene were utilized. By incorporating a 2-naphthol and a terminal alkyne, the chiral copper catalysts effect both Glaser-Hay coupling of the alkyne and oxidative asymmetric coupling of the 2-naphthol with remarkable chemoselectivity. The relative reaction rates of various moieties with the chiral catalysts follows the order: benzyl cyanides ? aryl alkynes > electron-rich 2-naphthols > electron-deficient 2-naphthols > alkyl alkynes. Because of high chemoselectivity, this approach is useful for the organized assembly of multifunctional substrates in a single operation. In all cases, no cross-coupling is observed between the alkyne and the 2-naphthol. This approach was thus applied to a set of highly functionalized precursors. In this third case, the biaryl coupling was performed first and a Glaser-Hay coupling was performed in a separate step to generate a highly functionalized polymer. In some cases, the resultant chiral polymers exhibit very large optical rotations.