1434152-52-9

Upstream product

• 1434152-51-8 1,3,4-tri-O-benzyl-6-O-acetyl-β-D-fructofuranosyl 2,3,4-tri-O-benzyl-α-D-glucopyranoside 
• 211678-08-9 p-methylphenyl 2,3,4,6-tetra-O-benzyl-1-thio-β-D-galactopyranoside 

Downstream Products

• 1434152-53-0 1,3,4-tri-O-benzyl-6-O-acetyl-β-D-fructofuranosyl 2,3,4-tri-O-benzyl-6-O-(2,3,4-tri-O-benzyl-6-O-triethylsilyl-α-D-galactopyranosyl)-α-D-glucopyranoside 

Relevant academic research and scientific papers

Synthesis of raffinose family oligosaccharides by regioselective de-O-benzylation with Co2(CO)8/Et3SiH/CO system

A convenient approach for synthesis of raffinose, stachyose, and verbascose using sucrose as the starting material is presented. The key step is the regioselective de-O-benzylation with Co2(CO)8/Et 3SiH/CO system, followed by a high α-selective glycosylation. The newly developed de-O-benzylation system is efficient in removing the primary benzyl groups of sucrose and raffinose under mild condition and with high selectivity. Using thioglycoside as donor, NIS/AgOTf as promoter and DTBMP as additive, glycosylation of acid labile sucrose substrate is achieved in high yield.