1434160-16-3

Basic information

• Product Name: 9-methoxy-1-(4-(tert-butyl)phenyl)-6,7-dihydro-5H-[1,2,3]triazolo[5',1':3,4][1,4]di-azepino[1,2-a]indol-6-ol
• Synonyms: 9-methoxy-1-(4-(tert-butyl)phenyl)-6,7-dihydro-5H-[1,2,3]triazolo[5',1':3,4][1,4]di-azepino[1,2-a]indol-6-ol
• CAS NO: 1434160-16-3
• Molecular Weight: 402.496
• Mol File: 1434160-16-3.mol

Chemical Properties

• CAS DataBase Reference: 9-methoxy-1-(4-(tert-butyl)phenyl)-6,7-dihydro-5H-[1,2,3]triazolo[5',1':3,4][1,4]di-azepino[1,2-a]indol-6-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 9-methoxy-1-(4-(tert-butyl)phenyl)-6,7-dihydro-5H-[1,2,3]triazolo[5',1':3,4][1,4]di-azepino[1,2-a]indol-6-ol(1434160-16-3)
• EPA Substance Registry System: 9-methoxy-1-(4-(tert-butyl)phenyl)-6,7-dihydro-5H-[1,2,3]triazolo[5',1':3,4][1,4]di-azepino[1,2-a]indol-6-ol(1434160-16-3)

Safety Data

• Hazardous Substances Data: 1434160-16-3(Hazardous Substances Data)

Upstream product

• 1434160-29-8 2-{2-[4-(tert-butyl)phenyl]ethynyl}-7-methoxy-1H-indole 
• 106-89-8 epichlorohydrin 

Relevant articles and documents

Microwave-assisted three-component domino reaction: Synthesis of indolodiazepinotriazoles

A microwave-assisted three-component protocol involving N-1 alkylation of 2-alkynylindoles with epichlorohydrin, ring opening of the epoxide with sodium azide, and an intramolecular Huisgen azide-internal alkyne 1,3-dipolar cycloaddition domino sequence has been described. The efficacy of the methodology has been demonstrated by treating various 2-alkynylindoles (aromatic/aliphatic) with epichlorohydrin and sodium azide furnishing annulated tetracyclic indolodiazepinotriazoles in satisfactory yields.