143425-79-0

Usage

Type of compound

Hydrazine derivative

Common use

Organic synthesis and pharmaceutical research

Synthesis method

Reaction of benzylhydrazine with mesityl methyl ketone

Physical state

Yellow liquid

Melting point

46-48°C

Boiling point

220-221°C at atmospheric pressure

Applications

Building block in the synthesis of pharmaceutical and agrochemical compounds

Additional uses

Intermediate in the production of dyes, pigments, and specialty chemicals

Upstream product

• 1585-16-6 2-chloromethyl-1,3,5-trimethylbenzene 
• 100-44-7 benzyl chloride 
• 143425-78-9 2,4,6-trimethylbenzylhydrazine 

Downstream Products

• 143425-74-5 1-(2',4',6'-trimethylphenyl)-2-phenylethane 
• 143425-69-8 N²-benzyl-N²-(2,4,6-trimethylbenzyl)methanesulfonohydrazide 

Relevant academic research and scientific papers

NITRENES. SYNTHESIS OF UNSYMMETRICAL BIBENZYLS

A method was developed for the synthesis of unsymmetrical bibenzyls by thermolysis of the potassium salts of methanesulfonohydrazides in dimethyl sulfoxide in the presence of 1-pentanethiol.The yields of the unsymmetrical bibenzyls and their derivatives c

N-NITRENES III. THE CAGE EFFECT AND THE FORMATION OF CROSSED PRODUCTS IN THE DISSOCIATION OF DI(ARYLMETHYL)AMINONITRENES

Symmetrically and unsymmetrically substituted di(arylmethyl)aminonitrenes, generated by thermolysis of the potassium salts of the respective methanesulfonohydrazides, dissociate in methanol, cyclohexanol, and dimethyl sulfoxide with the formation of nitrogen, 1,2-diarylethanes, and diarylmethanes.Unsymmetrically substituted di(arylmethyl)aminonitrenes form the products from crossed coupling of the arylmethyl radicals.The magnitude of the cage effect was determined for the pair of arylmethyl radicals, and the effect of the viscosity of the solvent on the yield of the cage recombination product was investigated.