143426-33-9Relevant academic research and scientific papers
Chemoenzymatic Approach to the Synthesis of the Antiviral Agents Penciclovir and Famciclovir in Isotopically Chiral Labelled Form
Sime, John T.,Barnes, Roger D.,Elson, Stephen W.,Jarvest, Richard L.,O'Toole, Kevin J.
, p. 1653 - 1658 (2007/10/02)
The antiviral agents penciclovir and famciclovir have been synthesised in isotopically chiral form.The synthesis of (+)-methyl 4-benzyloxy-2-(hydroxymethyl)butanoate 12a by use of enzymatic hydrolysis catalysed by the lipase from Candida cylindrac
