14344-01-5Relevant academic research and scientific papers
Sterically hindered benzophenones via rhodium-catalyzed oxidative arylation of aldehydes
Chuzel, Olivier,Roesch, Alexander,Genet, Jean-Pierre,Darses, Sylvain
, p. 7800 - 7802 (2008/12/22)
(Chemical Equation Presented) Efficient cross-coupling, allowing a straightforward access to congested benzophenones, between aromatic aldehydes and potassium aryltrifluoroborates, is described in the presence of a rhodium/tri-tert-butylphosphane catalyst system and acetone as cosolvent. The use of the stable phosphonium salts of tri-tert-butylphosphane prevented the use of highly oxidizable tri-tert-butylphosphane and allowed a careful control of the stoichiometry with the rhodium.
