14344-89-9

Basic information

• Product Name: bis(4-methoxyphenyl)(thiazol-2-yl)methanol
• Synonyms: bis(4-methoxyphenyl)(thiazol-2-yl)methanol
• CAS NO: 14344-89-9
• Molecular Weight: 327.404
• Mol File: 14344-89-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: bis(4-methoxyphenyl)(thiazol-2-yl)methanol(CAS DataBase Reference)
• NIST Chemistry Reference: bis(4-methoxyphenyl)(thiazol-2-yl)methanol(14344-89-9)
• EPA Substance Registry System: bis(4-methoxyphenyl)(thiazol-2-yl)methanol(14344-89-9)

Safety Data

• Hazardous Substances Data: 14344-89-9(Hazardous Substances Data)

Upstream product

• 1003-09-4 2-bromothiophene 
• 90-96-0 bis(p-methoxyphenyl)methanone 
• 3034-53-5 2-bromo-1,3-thiazole 

Downstream Products

• 13004-52-9 4,4'-thiazol-2-ylmethanediyl-bis-phenol 
• 14333-84-7 2-(4,4'-diacetoxy-benzhydryl)-thiazole 

Relevant articles and documents

Synthesis and biological evaluation of novel N-substituted nipecotic acid derivatives with an alkyne spacer as GABA uptake inhibitors

In this study, we present the synthesis and structure–activity relationships (SAR) of novel N-substituted nipecotic acid derivatives closely related to (S)-SNAP-5114 (2) in the pursuit of finding new and potent mGAT4 selective inhibitors. By the use of iminium ion chemistry, a series of new N-substituted nipecotic acid derivatives containing a variety of heterocycles, and an alkyne spacer were synthesized. Biological evaluation of the prepared compounds showed, how the inhibitory potency and subtype selectivity for the murine GABA transporters (mGATs) were influenced by the performed modifications.