143466-56-2Relevant academic research and scientific papers
Photocyclisation of enamides. Part 39. General strategy for the synthesis of pseudodistomins: Synthesis of triacetates of (±)-tetrahydropseudodistomin and proposed structures of pseudodistomins A and B
Naito, Takeaki,Yuumoto, Yoko,Kiguchi, Toshiko,Ninomiya, Ichiya
, p. 281 - 288 (2007/10/03)
A synthetic strategy of pseudodistomin was developed by first synthesizing the (±)-(2α,4β,5β)-5-amino-2-(3-hydroxypropyl)piperidin-4-ol 14 as a key intermediate via a route involving the reductive photocyclisation of enamide 5 followed by the introduction
First total synthesis of pseudodistomin tetrahydroacetate
Naito, Takeaki,Yuumoto, Yoko,Ninomiya, Ichiya,Kiguchi, Toshiko
, p. 4033 - 4036 (2007/10/02)
The first synthesis of tetrahydroacetate of pseudodistomin, a novel antineoplastic piperidine alkaloid, was achieved via the route involving the reductive photcyclization of enamide and α-acylamino radical allylation.
