143468-68-2

Upstream product

• 143468-56-8 (3S,3aR,4R,6aS)-4-(4-Methoxy-phenyl)-5,6a-dimethyl-2-oxo-3,3a,4,6a-tetrahydro-2H-cyclopenta[b]furan-3-carboxylic acid methyl ester 
• 143468-52-4 2-[(2E,4E)-5-(4-Methoxy-phenyl)-2,4-dimethyl-penta-2,4-dien-(E)-ylidene]-malonic acid monomethyl ester 
• 75101-99-4 (E)-3-(4-methoxyphenyl)-2-methylacrylaldehyde 
• 18795-82-9 2-propylidene malonic acid dimethyl ester 
• 143468-60-4 (3S,3aR,4R,6aS)-4-(4-Methoxy-phenyl)-5,6a-dimethyl-2-oxo-3,3a,4,6a-tetrahydro-2H-cyclopenta[b]furan-3-carboxylic acid 

Relevant academic research and scientific papers

Synthesis of 3,3a,4,6a-tetrahydro-6a-methyl-2-oxo-2H-cyclopenta[b]furans from (2E,4E,6E)-2-methoxycarbonyl-4-methylalka-2,4,6-trienoic acids

Thermal activation of 2-methoxycarbonyl-4-methylalka-2,4,6-trienoic acids 1 affords bicyclic α-carboxy-γ-lactone esters (methyl 3,3a,4,6a-tetrahydro-6a-methyl-2-oxo-2H-cyclopenta[b]furan-3-carboxyla tes, 2) in high yields.