14348-22-2 Usage
Uses
Used in Traditional Medicine:
CNIDILIN is used as a therapeutic agent for treating various conditions such as headache, toothache, abscess, furunculosis, and acne. Its effectiveness in alleviating pain and reducing inflammation makes it a popular choice for these applications.
Used in Pain Management:
CNIDILIN is utilized as an analgesic agent, particularly for headache and toothache. Its ability to reduce pain and inflammation makes it a viable option for managing these common ailments.
Used in Dermatology:
In the field of dermatology, CNIDILIN is used as a treatment for skin conditions such as abscess, furunculosis, and acne. Its anti-inflammatory and pain-relieving properties contribute to its effectiveness in addressing these skin issues.
Used in Herbal Medicine:
CNIDILIN is also employed in herbal medicine as a key ingredient in various formulations designed to target pain and inflammation. Its presence in Radix Angelicae dahuricae makes it a valuable addition to herbal remedies for a range of health concerns.
Check Digit Verification of cas no
The CAS Registry Mumber 14348-22-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,3,4 and 8 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 14348-22:
(7*1)+(6*4)+(5*3)+(4*4)+(3*8)+(2*2)+(1*2)=92
92 % 10 = 2
So 14348-22-2 is a valid CAS Registry Number.
14348-22-2Relevant academic research and scientific papers
Structure-activity relationships for naturally occurring coumarins as β-secretase inhibitor
Marumoto, Shinsuke,Miyazawa, Mitsuo
, p. 784 - 788 (2012/03/22)
The present study was demonstrated to evaluate the effects of naturally occurring coumarins (NOCs) including simple coumarins, furanocoumarins, and pyranocoumarins on the inhibition of β-secretase (BACE1) activity. Of 41 NOCs examined, some furanocoumarins inhibited BACE1 activity, but simple coumarins and pyranocoumarins did not affect. The most potent inhibitor was 5-geranyloxy-8-methoxypsoralen (31), which has an IC50 value of 9.9 μM. Other furanocoumarin derivatives, for example, 8-geranyloxy-5- methoxypsoralen (35), 8-geranyloxypsoralen (24), and bergamottin (18) inhibited BACE1 activity, with the IC50 values 25.0 μM. Analyses of the inhibition mechanism by Dixon plots and Cornish-Bowden plots showed that compounds 18, 31 and 35 were mixed-type inhibitor. The kinetics of inhibition of BACE1 by coumarins 24 was non-competitive inhibitors.
