143520-19-8

Basic information

• Product Name: 2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSYL N,N,N',N'-TETRAMETHYLPHOSPHORODIAMIDATE
• Synonyms: 2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSYL N,N,N',N'-TETRAMETHYLPHOSPHORODIAMIDATE;Ca.20%inbenzene;2,3,4,6-Tetra-O-benzyl-alpha-D-glucopyranosyl N,N,N',N'-Tetramethylphosphorodiamidate (ca. 20% in Benzene);2,3,4,6-Tetra-O-benzyl-alpha-D-glucopyranosyl N,N,N',N'-Tetramethylphosphorodiamidate (ca. 20% in Be;2,3,4,6-Tetra-O-benzyl-α-D-glucopyranosyl N,N,N',N'-TetraMethylphosphorodiaMidate (ca. 20% in Benzene)
• CAS NO: 143520-19-8
• Molecular Formula: C₃₈H₄₇N₂O₇P
• Molecular Weight: 674.76
• Product Categories: Biochemistry;Glucose;Glycosyl Donors;O-Substituted Sugars;Sugars
• Mol File: 143520-19-8.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Storage Temp.: Refrigerator
• CAS DataBase Reference: 2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSYL N,N,N',N'-TETRAMETHYLPHOSPHORODIAMIDATE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSYL N,N,N',N'-TETRAMETHYLPHOSPHORODIAMIDATE(143520-19-8)
• EPA Substance Registry System: 2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSYL N,N,N',N'-TETRAMETHYLPHOSPHORODIAMIDATE(143520-19-8)

Safety Data

• RIDADR: 1114
• HazardClass: 3
• PackingGroup: II
• Hazardous Substances Data: 143520-19-8(Hazardous Substances Data)

Usage

Uses

2,3,4,6-Tetra-O-benzyl-alpha-D-glucopyranosyl N,N,N’,N’-tetramethylphosphorodiamidate (CAS# 143520-19-8) is a carbohydrate used in the synthesis of oligosaccharides acting as a glycosyl acceptor with its phosphorous moiety acting as a leaving group.

Upstream product

• 4291-69-4 2,3,4,6-Tetra-O-benzyl-D-glucopyranose 
• 1605-65-8 N,N,N',N'-Tetramethylphosphorodiamidic chloride 

Downstream Products

• 55094-26-3 methyl 2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl-(1-6)-2,3,4-tri-O-benzyl-α-D-glucopyranoside 
• 56632-57-6 methyl O-2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl-(1->6)-2,3,4-tri-O-benzyll-α-D-glucopyranoside 
• 84799-76-8 methyl O-(2,3,4,6-tetra-O-benzyl-D-glucopyranosyl)-(1-4)-2,3,6-tri-O-benzyl-α-D-glucopyranoside 
• 193953-65-0 C₆₅H₆₉N₂O₁₅P 
• 193953-66-1 C₆₅H₇₅N₂O₁₂P 
• 193953-68-3 C₆₅H₆₁N₂O₁₉P 
• 193953-64-9 C₄₇H₅₃N₂O₁₀PSi 
• 193953-61-6 2,3,4-tri-O-benzoyl-α-D-glucopyranosyl tetramethylphosphoroamidate 
• 193953-63-8 C₂₆H₄₁N₂O₇PSi 
• 100648-82-6 2,3,4,6-Tetra-O-benzyl-1-O-(2-chlorobenzoyl)-D-glucopyranose 
• 70849-14-8 (2R,3R,4S,5R)-3,4,5-Tris-benzyloxy-2-benzyloxymethyl-6-[(3S,5S,8R,9S,10S,13R,14S,17R)-17-((R)-1,5-dimethyl-hexyl)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-3-yloxy]-tetrahydro-pyran 
• 208523-33-5 cholesteryl α- and β-2,3,4,6-tetra-O-benzyl-D-glucosides 

Relevant articles and documents

Oligosaccharide synthesis based on glycosyl donors and accepters carrying phosphorus-containing leaving groups

Efficient synthetic strategy for oligosaccharides has been developed by exploiting the difference in anomeric reactivity between glycosyl donors and acceptors carrying phosphorus-containing leaving groups, wherein, the tetramethylphosphoroamidate group plays a pivotal role as anomeric protective group as well as leaving group.