143536-22-5Relevant academic research and scientific papers
Nonclassical Mechanism in the Cyclodehydration of Diols Catalyzed by a Bifunctional Iridium Complex
González Miera, Greco,Bermejo López, Aitor,Martínez-Castro, Elisa,Norrby, Per-Ola,Martín-Matute, Belén
, p. 2631 - 2636 (2019)
1,4- and 1,5-diols undergo cyclodehydration upon treatment with cationic N-heterocyclic carbene (NHC)–IrIII complexes to give tetrahydrofurans and tetrahydropyrans, respectively. The mechanism was investigated, and a metal-hydride-driven pathway was proposed for all substrates, except for very electron-rich ones. This contrasts with the well-established classical pathways that involve nucleophilic substitution.
AN IMPROVED METHOD FOR THE GENERATION OF ORGANOZINC CARBENOIDS AND ITS APLLICATION IN DICARBONYL COUPLING REACTIONS
Afonso, Carlos A. M.,Motherwell, William B.,O'Shea, Dennis M.,Roberts, Lee R.
, p. 3899 - 3902 (2007/10/02)
Reaction of aromatic aldehydes and certain α,β-unsatured carbonyl compounds with 1,2-bis(chlorodimethylsilyl)ethane and zinc leads to products of symmetrical dicarbonyl coupling. Key words: Dicarbonyl Coupling; 1,2-bis(chlorodimethylsilyl)ethane and Zinc
