143539-75-7

Upstream product

• 143539-73-5 (3R,5S,8S,9R,10S,13R,14S,17R)-17-((R)-1,5-Dimethyl-hexyl)-9-fluoro-3-hydroxy-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-11-one 
• 143539-80-4 Acetic acid (3R,5S,8S,9R,10S,11S,13R,14S,17R)-17-((R)-1,5-dimethyl-hexyl)-9-fluoro-11-hydroxy-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-3-yl ester 
• 101836-11-7 Nicotinic acid (3R,5S,8R,9S,10S,13R,14S,17R)-17-((R)-1,5-dimethyl-hexyl)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-3-yl ester 
• 143539-68-8 C₂₉H₄₈O₃ 
• 37772-32-0 cholest-9(11)-en-3α-ol 
• 37772-03-5 Cholest-Δ⁹⁽¹¹⁾-3-en-3α-yl acetate 
• 80-97-7 Cholestanol 

Downstream Products

• 143539-78-0 4'-Iodo-biphenyl-3-carboxylic acid (3R,5S,8S,9R,10S,13S,14S)-9-fluoro-10,13-dimethyl-11,17-dioxo-hexadecahydro-cyclopenta[a]phenanthren-3-yl ester 

Relevant academic research and scientific papers

Chemical degradation of steroid side chains. Efficient conversion of cholestanol to corticosteroid intermediates.

17-Chlorosteroids, produced by template-directed halogenation of 9-fluoro 11-oxygenated cholestanols that are themselves produced by template methods, are converted to their 17-keto analogs in high yields (85-91%) after HCl elimination with DBU, followed by ozonolysis.