143539-87-1Relevant articles and documents
Stereocontrolled addition of 2-lithiothiazole to the nitrone derived fromD-glyceraldehyde acetonide. A revision and extension
Dondoni, Alessandro,Franco, Santiago,Merchant, Francisco Luis,Merino, Pedro,Tejero, Tomas
, p. 5475 - 5478 (1993)
The sense of diastereoselective addition of 2-lithiothiazole la to the nitrone 2 derived from Dglyceraldehyde is reversed by the use of Lewis acids (Et2AlCl, TiCl4) as complexing agents; the configuration of the hydroxylam
Stereoselective aminohomologation of chiral α-alkoxy aldehydes via thiazole addition to nitrones. Application to the synthesis of N-acetyl-D-mannosamine
Dondoni,Junquera,Merchan,Merino,Tejero
, p. 4221 - 4224 (2007/10/02)
The addition of 2-lithiothiazole to nitrones derived from D-glyceraldehyde and D-arabinose affords anti-adducts from which α-amino aldehydes are revealed by thiazole-to-formyl deblocking. The methodology provides a new synthesis of N-acetyl D-mannosamine