143540-37-8

Basic information

• Product Name: 11-(1-methylpiperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine-8-carbonitrile
• CAS NO: 143540-37-8
• Molecular Formula: C₂₁H₂₁N₃
• Molecular Weight: 315.4115
• Mol File: 143540-37-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 497.6°C at 760 mmHg
• Flash Point: 254.7°C
• Density: 1.2g/cm³
• Vapor Pressure: 4.9E-10mmHg at 25°C
• Refractive Index: 1.647
• CAS DataBase Reference: 11-(1-methylpiperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine-8-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 11-(1-methylpiperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine-8-carbonitrile(143540-37-8)
• EPA Substance Registry System: 11-(1-methylpiperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine-8-carbonitrile(143540-37-8)

Safety Data

• Hazardous Substances Data: 143540-37-8(Hazardous Substances Data)

Upstream product

• 143540-50-5 8-cyano-6,11-dihydro-11-(1-methyl-4-piperidyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol 

Relevant articles and documents

Benzo[5,6]cyclohepta[1,2-B]pyridine derivatives and antiallergic agents comprising same

Benzo[5,6]cyclohepta[1,2-b]pyridine derivatives of the following formula: STR1 wherein R1 represents a cyano, carbamoyl, alkylsulfoxy, alkylsulfonyl, tetrazolyl or sulfonic acid group, and R2 represents a hydrogen atom, a cyano, phenyl, aralkyl, alkoxycarbonylalkyl, aminoalkylcarbamoylalkyl or lower alkyl group, or a group STR2 or --X--R4, X being an oxygen or sulfur atom, R3 standing for a hydrogen atom or a substituted or unsubstituted lower alkyl, phenyl or aralkyl group, and R4 being a substituted or unsubstituted lower alkyl, phenyl or aralkyl group or an aminoalkyl group, and salts thereof. Antiallergic and antihistamic agents containing one of the above derivatives or salts as an active ingredient are also described.