1435488-97-3

Upstream product

• 106-38-7 para-bromotoluene 
• 1435488-88-2 2-(4-methoxyphenyl)-1-methyl-6-phenyl-1H-imidazo[1,2-b]pyrazole 
• 106-43-4 para-chlorotoluene 
• 827-41-8 3-phenylpyrazol-5-amine 
• 1435488-85-9 2-(4-methoxyphenyl)-6-phenyl-1H-imidazo[1,2-b]pyrazole hydrochloride 
• 1435488-82-6 2-(5-amino-3-phenyl-1H-pyrazol-1-yl)-1-(4-methoxyphenyl)ethanone 
• 1435488-81-5 C₂₅H₂₁N₃O 
• 74-88-4 methyl iodide 
• 2632-13-5 2-Bromo-4'-methoxyacetophenone 

Downstream Products

• 1435488-80-4 2-(4-methoxyphenyl)-1-methyl-6-phenyl-3,7-di(4-tolyl)-1H-imidazo[1,2-b]pyrazole 

Relevant academic research and scientific papers

Efficient synthesis and first regioselective c-3 direct arylation of imidazo[1,2-b]pyrazoles

Highly regioselective: An efficient synthesis of the imidazo[1,2-b]pyrazole core has been developed, and the first regioselective palladium-catalyzed direct arylation of the C-3 position is described (see scheme). Good to excellent yields were obtained for a wide range of aryl partners with electron-rich and electron-poor substituents. This methodology allows rapid access to a large variety of imidazo[1,2-b]pyrazole products and could open the way to the design of new biologically active compounds. Copyright