143572-30-9

Upstream product

• 130386-85-5 (3aR,4S,5R,6aS)-5-benzoyloxy-4-[(t-butyldiphenylsiloxy)methyl]hexahydro-2H-cyclopenta[b]furan-2-one 
• 143572-26-3 (3aS,4S,6aS)-4-(tert-Butyl-diphenyl-silanyloxymethyl)-3-hydroxy-3,3a,4,6a-tetrahydro-cyclopenta[b]furan-2-one 
• 143572-27-4 (3aS,4S,6aS)-4-(tert-Butyl-diphenyl-silanyloxymethyl)-3,3a,4,6a-tetrahydro-2H-cyclopenta[b]furan-2,3-diol 
• 143572-28-5 Formic acid (1S,4S,5R)-4-(tert-butyl-diphenyl-silanyloxymethyl)-5-formyl-cyclopent-2-enyl ester 
• 84786-80-1 (3aR,4S,5R,6aS)-hexahydro-5-hydroxy-4-[(tert-butyldiphenylsilyloxy)methyl]-2H-cyclopenta[b]furan-2-one 
• 143572-25-2 (3aR,4S,6aS)-4-(tert-Butyl-diphenyl-silanyloxymethyl)-3,3a,4,6a-tetrahydro-cyclopenta[b]furan-2-one 
• 39746-00-4 (1S,5R,6S,7R)-7-benzoyloxy-6-hydroxymethyl-2-oxabicyclo[3.3.0]octan-3-one 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 143572-29-6 (1S,4S,5S)-4-(tert-Butyl-diphenyl-silanyloxymethyl)-5-hydroxymethyl-cyclopent-2-enol 
• 58479-61-1 tert-butylchlorodiphenylsilane 

Downstream Products

• 143678-59-5 (1R,4S,5R)-9-(4,5-Bishydroxymethylcyclopent-2-en-1-yl)-9H-adenine 
• 143572-31-0 9-[(1R,4S,5R)-5-(tert-Butyl-dimethyl-silanyloxymethyl)-4-(tert-butyl-diphenyl-silanyloxymethyl)-cyclopent-2-enyl]-6-chloro-9H-purine 

Relevant academic research and scientific papers

Synthesis of (1R, 4S, 5R)-9-(4,5-bishydroxy-methylcyclopent-2-en-1-yl)-9H-adenine [(-)-BCA] and selective inhibition of human immunodeficiency virus

(1R,4S,5R)-9(4,5-Bishydroxymethylcyclopent-2-en-1-yl)-9H-adenine [(-)-BCA] has been synthesized from (-)-Corey lactone in 11 steps and shown to have potent and selective effects against human immmunodeficiency virus type 1. The result demonstrated that th