143576-69-6Relevant academic research and scientific papers
New copper complexes inducing bimodal death through apoptosis and autophagy in A549 cancer cells
Chen, Ming,Chen, Zhen-Feng,Choudhary, Muhammad Iqbal,Gul, Noor Shad,Hou, Cheng,Huang, Ke-Bin,Khan, Taj-Malook,Liang, Hong
, (2020)
Two copper complexes, Cu1 (CuL1Cl2, L1 = 2-(6,7-dimethoxyisoquinolin-1-yl) aniline) and Cu2 (CuL2Cl2, L2 = 2-(6-methoxyisoquinolin-1-yl) aniline), were synthesized and characterized. These
Divergent Syntheses of Pyridoacridine Alkaloids via Palladium-Catalyzed Reductive Cyclization with Nitro-Biarenes
Bian, Changhao,Liao, Hongze,Lin, Hou-Wen,Liu, Bo,Wang, Shuping
supporting information, p. 1905 - 1910 (2021/06/07)
A divergent and novel protocol for the preparation of both pyrido[2,3,4-kl]acridine and pyrido[4,3,2-kl]acridine alkaloids was developed. This method featured the remote palladium-catalyzed reductive cyclization with Mo(CO)6 as reductant. A wide range of substrates including three types of nitro arenes were tolerated and afforded corresponding products in good to excellent yields. This method has been successfully applied to the total synthesis of norsegoline, styelsamine C and the skeleton of necatorone.
Synthesis of 1-(2-aminophenyl)isoquinolines and the biological activity of their cis-dichloro platinum(II) complexes
Von Nussbaum, Franz,Miller, Bernhard,Wild, Stefan,Hilger, Christoph S.,Schumann, Susanne,Zorbas, Haralabos,Beck, Wolfgang,Steglich, Wolfgang
, p. 3478 - 3485 (2007/10/03)
The broad biological effects of isoquinolines prompted us to use them as chelating, nonleaving ligands in cis-platinum(II) antitumor complexes. The synthesis of several 1-(2-aminophenyl)isoquinoline derivatives with different levels of hydrogenation and v
