143585-48-2Relevant academic research and scientific papers
MgBr2-promoted enantioselectIVe aryl addition of ArTi(OiPr)3 to ketones catalyzed by a titanium(IV) catalyst of N,N′-sulfonylated (1R,2R)-cyclohexane-1,2-diamine
Shu, Chao-Chi,Zhou, Shuangliu,Gau, Han-Mou
, p. 98391 - 98398 (2015/12/04)
MgBr2-promoted asymmetric addition of ArTi(OiPr)3 to ketones catalyzed by a titanium catalyst of N,N′-sulfonylated (1R,2R)-cyclohexane-1,2-diamines is reported, and results showed that the chiral N,N′-sulfonylated cyclohex
Practical enantioselective synthesis of β-lactones catalyzed by aluminum bissulfonamide complexes
Kull, Thomas,Peters, Rene
, p. 1647 - 1652 (2008/02/11)
The development of an efficient and practical aluminum-bissulfonamide complex catalyzed enantioselective formation of β-lactones by [2+2] cycloaddition of ketene (generated in situ from acetyl bromide by dehydrobromination) with various α-unbranched and -
Catalytic enantioselective cyclopropanation with bis(halomethyl) zinc reagents. II. The effect of promoter structure on selectivity
Denmark, Scott E.,Christenson, Beritte L.,O'Connor, Stephen P.
, p. 2219 - 2222 (2007/10/02)
The catalytic, enantioselective cyclopropanation of cinnamyl alcohol has been accomplished with bis (iodomethyl)zinc in the presence of chiral bis(sulfonamides) derived from cyclohexanediamine. An extensive survey of diamine and sulfonamide structure has revealed a marked sensitivity to the spatial relationship of the amine groups, but only a modest dependence on the sulfonamide residue.
Stereoselective Protonation of Carbanions, 4. Enantioselective Protonation of Lactone Enolates
Gerlach, Uwe,Haubenreich, Thomas,Huenig, Siegfried
, p. 1969 - 1980 (2007/10/02)
The prochiral lithium enolates derived from the five-membered lactones rac-1 and rac-2 were protonated by 37 OH- and 21 NH-chiral proton sources in THF at -78 deg C.The enantioselectivities, determined directly from the reaction mixture by chiral HPLC, ar
A Catalytic Enantioselective Reaction Using a C2-Symmetric Disulfonamide as a Chiral Ligand: Alkylation of Aldehydes Catalyzed by Disulfonamide-Ti(O-i-Pr)4-Dialkyl Zinc System
Takahashi, Hideyo,Kawakita, Takashi,Ohno, Masaji,Yoshioka, Masato,Kobayashi, Susumu
, p. 5691 - 5700 (2007/10/02)
Excellent enantioselective alkylation of aldehydes with dialkylzinc has been developed.This methodology is based on the concept of modifying the Lewis acid with a C2-symmetric, electron-withdrawing disulfonamide.The chiral Lewis acid catalysts used in the present study are the titanium complexes, prepared in-situ from disulfonamide and Ti(O-i-Pr)4.Key Words: Chiral disulfonamide; chiral titanium complex; enantioselective alkylation; dialkyl zinc; catalytic reaction
