1435938-50-3Relevant academic research and scientific papers
Pd/C-catalyzed, copper-free Sonogashira coupling: One-pot synthesis of 1-aryl-4-(2-phenylethynyl)[1,2,4]triazolo[4,3-a]quinoxalines in water
Bakherad, Mohammad,Jajarmi, Saeideh
, p. 885 - 890 (2013/07/05)
Copper-free, Pd/C-catalyzed, one-pot reaction of 2,3-dichloroquinoxaline with hydrazine hydrate, bromine, phenylacetylene, and a variety of aldehydes provides an efficient and direct method for the preparation of 1-aryl-4-(2-phenylethynyl)[1,2,4]triazolo[4,3-a]quinoxalines in water at 70 C. This methodology involves the use of inexpensive reagents or catalysts, and thus permits a new and practical access to triazolo[4,3-a]quinoxalines.
