143602-39-5

Basic information

• Product Name: Ethyl-[4-(3-methylamino-propyl)-5-(4-nitro-phenyl)-thiazol-2-yl]-amine; hydrobromide
• CAS NO: 143602-39-5
• Molecular Weight: 401.327
• Mol File: 143602-39-5.mol

Chemical Properties

• CAS DataBase Reference: Ethyl-[4-(3-methylamino-propyl)-5-(4-nitro-phenyl)-thiazol-2-yl]-amine; hydrobromide(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl-[4-(3-methylamino-propyl)-5-(4-nitro-phenyl)-thiazol-2-yl]-amine; hydrobromide(143602-39-5)
• EPA Substance Registry System: Ethyl-[4-(3-methylamino-propyl)-5-(4-nitro-phenyl)-thiazol-2-yl]-amine; hydrobromide(143602-39-5)

Safety Data

• Hazardous Substances Data: 143602-39-5(Hazardous Substances Data)

Upstream product

• 826-41-5 N-Methyl-2,2-diethoxypyrrolidine 
• 143602-53-3 1-Ethyl-2-(4-nitro-benzyl)-isothiourea; hydrobromide 

Relevant articles and documents

Synthesis of 4-(ω-aminoalkyl)- or 4-(ω-lactamiminoalkyl)thiazoles by ring chain transformation of isothioureas with lactam derivatives

CH-Acidic isothioureas 1 react with lactam acetals 2 at the unsubstituted N-atom as well as at the acidic S-methylene group giving 4-(ω-aminoalkyl)thiazoles 6. The latter are further transformed to 4-(ω-lactamiminoalkyl)thiazoles 8, if lactim ethers 3 are used in reactions with isothioureas 1.