14364-09-1

Basic information

• Product Name: 1-[3-(4-Hydroxy-3,5-diMethoxyphenyl)-2-propenoate]
• Synonyms: 1-[3-(4-Hydroxy-3,5-diMethoxyphenyl)-2-propenoate];Sinapic Acid Acyl-β-D-glucoside
• CAS NO: 14364-09-1
• Molecular Formula: C₁₇H₂₂O₁₀
• Molecular Weight: 386.35
• Product Categories: Aromatic;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals
• Mol File: 14364-09-1.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility: Methanol (Slightly)
• Stability: Moisture Sensitive
• CAS DataBase Reference: 1-[3-(4-Hydroxy-3,5-diMethoxyphenyl)-2-propenoate](CAS DataBase Reference)
• NIST Chemistry Reference: 1-[3-(4-Hydroxy-3,5-diMethoxyphenyl)-2-propenoate](14364-09-1)
• EPA Substance Registry System: 1-[3-(4-Hydroxy-3,5-diMethoxyphenyl)-2-propenoate](14364-09-1)

Safety Data

• Hazardous Substances Data: 14364-09-1(Hazardous Substances Data)

Usage

Uses

Sinapic Acid Acyl-β-D-glucoside is a metabolite of Sinapic Acid (S486800).

Upstream product

• 133-89-1 UDP-glucose 
• 530-59-6 sinapinic acid 
• 830322-97-9 2,3,4,6-tetra-O-chloroacetylglucosyl trichloroacetimidate 
• 30572-07-7 2,3,4,6-tetra-O-chloroacetyl-D-glucopyranose 
• 830322-96-8 1,2,3,4,6-penta-O-chloroacetyl-α,β-D-glucopyranose 
• 2492-87-7 4-nitrophenyl-β-D-glucoside 

Relevant articles and documents

Enzymology of UDP-Glucose:Sinapic Acid Glucosyltransferase from Brassica napus

UDP-glucose:sinapic acid glucosyltransferase (SGT; EC 2.4.1.120) was purified from 60-h-old seedlings of Brassica napus. The purifiod SGT appears to be a cytosolic monomeric polypeptide with a Mr of 42 kDa and a pI of 5. Kinetic analysis sugges

Engineering faster transglycosidases and their acceptor specificity

Transglycosidases are enzymes that have the potential to catalyze the synthesis of a wide range of high-value compounds starting from biomass-derived feedstocks. Improving their activity and broadening the substrate range are important goals to enable the widespread application of this family of biocatalysts. In this work, we engineered 20 mutants of the rice transglycosidase Os9BGlu31 and evaluated their catalysis in 462 reactions over 18 different substrates. This allowed us to identify mutants that expanded their substrate range and showed high activity, including W243L and W243N. We also developed double mutants that show very high activity on certain substrates and exceptional specificity towards hydrolysis, such as L241D/W243N. In order to guide a more general use of Os9BGlu31 variants as transglycosylation catalysts, we built cheminformatics models based on topological descriptors of the substrates. These models showed useful predictive potential on the external validation set and are allowing the identification of efficient catalytic routes to novel phytohormone and antibiotic glucoconjugates of interest.