1436406-56-2Relevant academic research and scientific papers
Synthesis and structure revision of the C43-C67 part of amphidinol 3
Ebine, Makoto,Kanemoto, Mitsunori,Manabe, Yoshiyuki,Konno, Yosuke,Sakai, Ken,Matsumori, Nobuaki,Murata, Michio,Oishi, Tohru
supporting information, p. 2846 - 2849 (2013/07/26)
Stereoselective synthesis of the C43-C67 part of amphidinol 3 (AM3) and its C51-epimer was achieved starting from a common intermediate corresponding to the tetrahydropyran moiety of AM3, via asymmetric oxidations and Julia-Kocienski olefination. By comparing NMR data of the synthetic specimens with those of AM3, the absolute configuration at C51 of AM3 was revised from R to S.
