1436430-75-9Relevant academic research and scientific papers
Cobalt-Catalyzed Carbonylative Cyclization of Pyridinyl Diazoacetates for the Synthesis of Pyridoisoquinolinones
Baek, Yonghyeon,Kim, Sunghwa,Jeon, Bongkeun,Lee, Phil Ho
, p. 104 - 107 (2016)
Dicobalt octacarbonyl-catalyzed carbonylative cyclization of pyridinyl diazoacetates is developed for the synthesis of pyridoisoquinolinones under mild conditions (room temperature) in a carbon monoxide atmosphere. Moreover, a synthetic method for various pyridoisoquinolinones from ethylpyridinyl aryl acetates is demonstrated through diazotization using TsN3 and DBU followed by Co-catalyzed carbonylation to generate ketene intermediates, which can subsequently undergo intramolecular cyclization under mild conditions in a carbon monoxide atmosphere in a semi-one-pot fashion.
Synthesis of Pyridoisoindoles through Diazotization Followed by Intramolecular Cyclization from Pyridinylarylacetates in One Pot
Kim, Cheol-Eui,Baek, Yonghyeon,Kim, Sung Hong,Lee, Phil Ho
, p. 2903 - 2912 (2015)
A robust synthetic method for a variety of pyridoisoindoles from pyridinylarylacetates has been developed through diazotization using 4-methylbenzenesulfonyl azide and 1,8-diazabicyclo[5.4.0]undec-7-ene followed by intramolecular cyclization via eliminati
Rhodium(III)-catalyzed azacycle-directed intermolecular insertion of arene C-H bonds into α-diazocarbonyl compounds
Yu, Xinzhang,Yu, Songjie,Xiao, Jian,Wan, Boshun,Li, Xingwei
, p. 5444 - 5452 (2013/07/25)
Cp*Rh(III)-catalyzed intermolecular C-C couplings between activated α-diazocarbonyl compounds and arenes bearing a range of azacyclic directing groups have been achieved. This catalytic alkylation reaction operates under mild conditions with good functional group tolerance.
