1436461-06-1

Basic information

• Product Name: ethyl 2-amino-3a-(4-bromophenyl)-1-carbamoyl-3-cyano-6-methyl-3a,4-dihydro-1H-pyrrolo[1,2-b]pyrazole-5-carboxylate
• Synonyms: ethyl 2-amino-3a-(4-bromophenyl)-1-carbamoyl-3-cyano-6-methyl-3a,4-dihydro-1H-pyrrolo[1,2-b]pyrazole-5-carboxylate
• CAS NO: 1436461-06-1
• Molecular Weight: 432.277
• Mol File: 1436461-06-1.mol

Chemical Properties

• CAS DataBase Reference: ethyl 2-amino-3a-(4-bromophenyl)-1-carbamoyl-3-cyano-6-methyl-3a,4-dihydro-1H-pyrrolo[1,2-b]pyrazole-5-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-amino-3a-(4-bromophenyl)-1-carbamoyl-3-cyano-6-methyl-3a,4-dihydro-1H-pyrrolo[1,2-b]pyrazole-5-carboxylate(1436461-06-1)
• EPA Substance Registry System: ethyl 2-amino-3a-(4-bromophenyl)-1-carbamoyl-3-cyano-6-methyl-3a,4-dihydro-1H-pyrrolo[1,2-b]pyrazole-5-carboxylate(1436461-06-1)

Safety Data

• Hazardous Substances Data: 1436461-06-1(Hazardous Substances Data)

Upstream product

• 94127-05-6 ethyl 3-[(aminocarbonyl)diazenyl]but-2-enoate 
• 26088-78-8 2-[1-(4-bromophenyl)ethylidene]malononitrile 

Relevant articles and documents

Synthesis of densely functionalized 3a,4-dihydro-1 H-pyrrolo[1,2- b]pyrazoles via base mediated domino reaction of vinyl malononitriles with 1,2-diaza-1,3-dienes

A domino reaction of vinyl malononitriles (VMs) with 1,2-diaza-1,3-dienes (DDs) produce unprecedented 3a,4-dihydro-1H-pyrrolo[1,2-b]pyrazole systems in a chemo-, regio-, and stereoselective fashion. This base promoted (DIPEA) one-pot transformation involving multiple steps constructs one new C-C bond, two C-N bonds, and two new fused heterocyclic rings with total atom economy.