1436631-16-1Relevant academic research and scientific papers
Selective CB2 agonists with anti-pruritic activity: Discovery of potent and orally available bicyclic 2-pyridones
Kusakabe, Ken-Ichi,Iso, Yasuyoshi,Tada, Yukio,Sakagami, Masahiro,Morioka, Yasuhide,Chomei, Nobuo,Shinonome, Satomi,Kawamoto, Keiko,Takenaka, Hideyuki,Yasui, Kiyoshi,Hamana, Hiroshi,Hanasaki, Kohji
, p. 3154 - 3163 (2013)
The CB2 receptor has emerged as a potential target for the treatment of pruritus as well as pain without CB1-mediated side effects. We previously identified 2-pyridone derivatives 1 and 2 as potent CB2 agonists; however, this series of compounds was found
