1436688-83-3

Upstream product

• 1436688-80-0 3-nitro-7-phenylquinoline-2,4-diol 
• 1436688-77-5 7-bromo-3-nitroquinoline-2,4-diol 

Downstream Products

• 1436688-86-6 2-chloro-3-nitro-7-phenylquinolin-4-amine 
• 1436688-89-9 2-chloro-7-phenylquinoline-3,4-diamine 
• 1232148-54-7 4-chloro-2-(2-chloro-6-fluorophenyl)-7-phenylimidazo[4,5-c]quinoline 
• 1436688-92-4 2-(2-chloro-6-methylphenyl)-7-phenylimidazo[4,5-c]quinolin-4(5H)-one 
• 1436688-95-7 2-(2-chloro-6-(trifluoromethyl)phenyl)-7-phenylimidazo[4,5-c]quinolin-4(5H)-one 
• 1436688-98-0 2-(2-chloro-6-nitrophenyl)-7-phenylimidazo[4,5-c]quinolin-4(5H)-one 
• 1232149-29-9 2-(2-chloro-6-fluorophenyl)-7-phenylimidazo[4,5-c]quinolin-4(5H)-one 
• 1436689-03-0 4-chloro-2-(2-chloro-6-methylphenyl)-7-phenylimidazo[4,5-c]quinoline 
• 1436689-07-4 4-chloro-2-(2-chloro-6-(trifluoromethyl)phenyl)-7-phenylimidazo[4,5-c]quinoline 
• 1436689-11-0 4-chloro-2-(2-chloro-6-nitrophenyl)-7-phenylimidazo[4,5-c]quinoline 

Relevant academic research and scientific papers

7-Phenyl-imidazoquinolin-4(5H)-one derivatives as selective and orally available mPGES-1 inhibitors

To identify compounds with strong mPGES-1 inhibitory activity and clear in vitro ADME profile, we optimized the lead compound 1 by carrying our substitutions at the C(7)- and C(8)-positions. Replacement of the bromine atom of 1 with various substituents l