1436849-26-1Relevant articles and documents
Cobalt-promoted selective arylation of benzamides and acrylamides with arylboronic acids
Hu, Liang,Gui, Qingwen,Chen, Xiang,Tan, Ze,Zhu, Gangguo
supporting information, p. 11070 - 11075 (2016/12/09)
A novel cobalt-promoted arylation of aryl C-H bonds with arylboronic acids has been realized by using 8-aminoquinoline as the directing group. The reaction tolerated a wide variety of functional groups and diversely substituted ortho-arylated benzamides were efficiently synthesized in good to excellent yields. Even though a catalytic amount of a Co-salt was enough to effect the transformation, better yields were obtained with a stoichiometric amount of the Co-salt. A notable feature of this newly developed protocol is that acrylamides, which cannot be arylated using copper salts as the promoter, can also be efficiently arylated. In addition, the stereochemistry of these arylation products can be largely retained under the standard conditions.
METHOD OF PRODUCING COUPLING COMPOUND BY IRON CATALYST
-
Page/Page column 24, (2016/10/07)
PROBLEM TO BE SOLVED: To provide a novel method that makes it possible to produce a wide variety of coupling compounds with good environmental harmony without using organic halogen compounds, and in which large-scale synthesis can be conducted at a low co
Iron-catalyzed C(sp2)-H bond functionalization with organoboron compounds
Shang, Rui,Ilies, Laurean,Asako, Sobi,Nakamura, Eiichi
supporting information, p. 14349 - 14352 (2014/12/11)
We report here that an iron-catalyzed directed C-H functionalization reaction allows the coupling of a variety of aromatic, heteroaromatic, and olefinic substrates with alkenyl and aryl boron compounds under mild oxidative conditions. We rationalize these results by the involvement of an organoiron(III) reactive intermediate that is responsible for the C-H bond-activation process. A zinc salt is crucial to promote the transfer of the organic group from the boron atom to the iron(III) atom.
