1436865-34-7Relevant academic research and scientific papers
Synthesis, structure, and antibacterial activity of aminobenzofuroxan and aminobenzofurazan
Galkina,Takhautdinova,Tudrii,Yusupova,Falyakhov,Pozdeev,Shulaeva,Kipenskaya,Sakhibullina,Krivolapov,Litvinov,Galkin,Cherkasov
, p. 591 - 597 (2013/06/26)
The amination of 4,6-dichloro-5,7-dinitrobenzofuroxan and 4,6-dichloro-5,7-dinitrobenzofurazan with dibenzylamine followed the aromatic nucleophilic substitution pattern (SNAr) and gave products of replacement of both chlorine atoms in the six-membered ring with elimination of hydrogen chloride. Regardless of the reactant ratio, 4,6-dichloro-5,7- dinitrobenzofuroxan was converted into 4,6-bis(dibenzylamino)-5,7- dinitrobenzofuroxan, whereas 4,6-dichloro-5,7-dinitrobenzofurazan under analogous conditions gave rise to unusual bisammonium derivative which lost proton from the amino group on C4 and benzyl group from the amino group on C6; as a result, the corresponding diamine with secondary and tertiary nitrogen atoms was obtained. The structure of the isolated compounds was determined by IR and NMR spectroscopy, elemental analysis, and X-ray analysis; their thermal stability was studied by simultaneous thermogravimetry and differential scanning calorimetry.
