(E)-(20R)-de-A,B-8-(bromomethylene)cholestan-25-ol is a chemical compound with a molecular formula of C27H43BrO, belonging to the class of cholestanols and being a derivative of cholesterol. As a sterol, it is a type of lipid that plays a crucial role in the normal function of cell membranes. (E)-(20R)-de-A,B-8-(bromomethylene)cholestan-25-ol features a bromomethylene group, which contributes to its reactivity and potential utility in organic synthesis and medicinal chemistry. However, it is essential to exercise caution when handling (E)-(20R)-de-A,B-8-(bromomethylene)cholestan-25-ol due to its potential reactivity and toxicity.
143705-63-9
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Basic information
- Product Name: (E)-(20R)-de-A,B-8-(bromomethylene)cholestan-25-ol
- Synonyms: (E)-(20R)-de-A,B-8-(bromomethylene)cholestan-25-ol
- CAS NO:143705-63-9
- Molecular Formula:
- Molecular Weight: 357.374
- EINECS: N/A
- Product Categories: N/A
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: N/A
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: (E)-(20R)-de-A,B-8-(bromomethylene)cholestan-25-ol(CAS DataBase Reference)
- NIST Chemistry Reference: (E)-(20R)-de-A,B-8-(bromomethylene)cholestan-25-ol(143705-63-9)
- EPA Substance Registry System: (E)-(20R)-de-A,B-8-(bromomethylene)cholestan-25-ol(143705-63-9)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 143705-63-9(Hazardous Substances Data)
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143705-63-9 Usage
Uses
Used in Organic Synthesis:(E)-(20R)-de-A,B-8-(bromomethylene)cholestan-25-ol is used as a reactive intermediate for the synthesis of various complex organic molecules. Its unique structure and reactivity make it a valuable building block in the development of novel compounds with specific applications.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, (E)-(20R)-de-A,B-8-(bromomethylene)cholestan-25-ol is utilized as a key component in the design and synthesis of new pharmaceuticals. Its structural similarity to cholesterol allows it to be used in the development of drugs targeting lipid metabolism and related diseases.
Used in Research and Development:
(E)-(20R)-de-A,B-8-(bromomethylene)cholestan-25-ol is also employed in research and development settings to study the effects of structural modifications on the biological activity of sterols. Understanding these effects can lead to the discovery of new therapeutic agents and a better understanding of lipid-related processes in the body.
Used in Pharmaceutical Industry:
(E)-(20R)-de-A,B-8-(bromomethylene)cholestan-25-ol is used as a starting material for the production of various pharmaceuticals, particularly those targeting cholesterol-related conditions. Its unique properties make it a promising candidate for the development of innovative treatments.
Used in Chemical Education:
In educational settings, (E)-(20R)-de-A,B-8-(bromomethylene)cholestan-25-ol can be used to demonstrate the principles of organic chemistry, particularly in the context of steroidal compounds and their synthesis. It provides a practical example of how structural modifications can influence the properties and applications of a molecule.
Check Digit Verification of cas no
The CAS Registry Mumber 143705-63-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,3,7,0 and 5 respectively; the second part has 2 digits, 6 and 3 respectively.Calculate Digit Verification of CAS Registry Number 143705-63:
(8*1)+(7*4)+(6*3)+(5*7)+(4*0)+(3*5)+(2*6)+(1*3)=119
119 % 10 = 9
So 143705-63-9 is a valid CAS Registry Number.
143705-63-9Upstream product
143705-63-9Downstream Products
- 32222-06-3 calcitriol
- 223437-60-3 (R)-6-{(1R,3aS,7aR)-4-[2-[(3S,4R,5R)-3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-4-methyl-2-methylene-cyclohex-(Z)-ylidene]-eth-(E)-ylidene]-7a-methyl-octahydro-inden-1-yl}-2-methyl-heptan-2-ol
- 140710-96-9 (1S),3(R)-bis<(tert-butyldimethylsilyl)oxy>-9,10-secocholesta-5(Z),7(E),10(19)-trien-25-ol
- 794516-08-8 (R)-6-{(1R,3aS,7aR)-4-[2-[(3R,4S,5R)-3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-4-[2-(tert-butyl-dimethyl-silanyloxy)-ethoxy]-2-methylene-cyclohex-(Z)-ylidene]-eth-(E)-ylidene]-7a-methyl-octahydro-inden-1-yl}-2-methyl-heptan-2-ol
- 357332-31-1 (R)-6-{(1R,3aS,7aR)-4-[2-[(3R,4S,5R)-3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-4-[3-(tert-butyl-dimethyl-silanyloxy)-propoxy]-2-methylene-cyclohex-(Z)-ylidene]-eth-(E)-ylidene]-7a-methyl-octahydro-inden-1-yl}-2-methyl-heptan-2-ol
- 794516-15-7 (R)-6-{(1R,3aS,7aR)-4-[2-[(3R,4S,5R)-3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-4-[4-(tert-butyl-dimethyl-silanyloxy)-butoxy]-2-methylene-cyclohex-(Z)-ylidene]-eth-(E)-ylidene]-7a-methyl-octahydro-inden-1-yl}-2-methyl-heptan-2-ol
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(E)-(20R)-de-A,B-8-(bromomethylene)cholestan-25-ol
