1437281-18-9Relevant academic research and scientific papers
2 -aryl quinoxaline compound with affinity with Tau protein as well as preparation method and application thereof (by machine translation)
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Paragraph 0036; 0169; 0170, (2020/12/30)
The invention provides 2 -arylquinoxaline compounds with affinity with Tau protein, and the structure is as shown in a formula (I). The invention further provides a preparation method of the compound of the formula (I). The compound can be directly used a
RADIOACTIVE FLUORINE-LABELED QUINOXALINE COMPOUND
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Paragraph 0084-0085, (2014/04/03)
Provided is a compound effective as a diagnostic imaging probe targeting amyloid and an agent for Alzheimer's disease diagnosis including the compound.
Structure-activity relationships and in vivo evaluation of quinoxaline derivatives for PET imaging of β-amyloid plaques
Yoshimura, Masashi,Ono, Masahiro,Matsumura, Kenji,Watanabe, Hiroyuki,Kimura, Hiroyuki,Cui, Mengchao,Nakamoto, Yuji,Togashi, Kaori,Okamoto, Yoko,Ihara, Masafumi,Takahashi, Ryosuke,Saji, Hideo
supporting information, p. 596 - 600 (2013/07/26)
This letter describes the synthesis, structure-activity relationships, and in vivo evaluation of a new series of 2-phenylquinoxaline (PQ) derivatives for imaging β-amyloid (Aβ) plaques in Alzheimer's disease (AD). In experiments in vitro, the affinity of
