143767-97-9

Basic information

• Product Name: 3-Butyn-2-amine, 2-methyl-4-phenyl-
• CAS NO: 143767-97-9
• Molecular Formula: C11H13N
• Molecular Weight: 159.231
• Mol File: 143767-97-9.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: 3-Butyn-2-amine, 2-methyl-4-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Butyn-2-amine, 2-methyl-4-phenyl-(143767-97-9)
• EPA Substance Registry System: 3-Butyn-2-amine, 2-methyl-4-phenyl-(143767-97-9)

Safety Data

• Hazardous Substances Data: 143767-97-9(Hazardous Substances Data)

Upstream product

• 1612-03-9 3-methyl-1-phenyl-but-1-yne 
• 591-50-4 iodobenzene 
• 598-23-2 3-methyl-but-1-yne 
• 2978-58-7 1,1-dimethylprop-3-ynylamine 

Downstream Products

• 1308330-80-4 N-(1,1-dimethyl-4-phenyl-2-propyn-1-yl)benzamide 
• 114564-88-4 (Z)-5-benzylidene-4,4-dimethyl-2-phenyl-4,5-dihydrooxazole 

Relevant articles and documents

Efficient and Reusable Metal–Organic Framework Catalysts for Carboxylative Cyclization of Propargylamines with Carbon Dioxide

Carbon dioxide (CO2) capture and transformation are important for decreasing the concentration of atmospheric CO2. To effectively capture CO2 and further fix it into valuable chemical products, functionalized dynamic metal–organic frameworks (MOFs) have been utilized not only because of their inherent cavity for accommodating CO2 but also owing to their reversible structural transformations in response to external stimuli for regulating the reaction. Herein, we report a dynamic and functional MOF [Cd3(L)2(BDC)3]2?16 DMF (MOF-1 a; DMF=N,N-dimethylformamide) achieved by reaction of the amino tripodal imidazole ligand N1-(4-(1 H-imidazol-1-yl)benzyl)-N1- (2-aminoethyl)ethane-1,2-diamine (L) and 1,4-benzenedicarboxylic acid (H2BDC) with cadmium salt. MOF-1 a not only shows unprecedented high catalytic activity [initial turnover number (TON) up to 9300] and broad substrate scope for the carboxylative cyclization of propargylamines with CO2, but also can be switched on and off upon reversible structural transformation owing to its dynamic five-fold interpenetrating structure. Further studies demonstrate that MOF-1 a shows selective catalytic properties depending on the size of substrates, similarly to sophisticated biological systems.

An Enzymatic Platform for Primary Amination of 1-Aryl-2-alkyl Alkynes

Propargyl amines are versatile synthetic intermediates with numerous applications in the pharmaceutical industry. An attractive strategy for efficient preparation of these compounds is nitrene propargylic C(sp3)-H insertion. However, achieving this reacti

Benzene-1,3,5-triyl Triformate (TFBen)-Promoted Palladium-Catalyzed Carbonylative Synthesis of 2-Oxo-2,5-dihydropyrroles from Propargyl Amines

In this letter, we developed a palladium-catalyzed procedure for the cyclocarbonylation of propargyl amines. Benzene-1,3,5-triyl triformate (TFBen) has been explored as the CO source and also as the key promotor. Various substituted 2-oxo-dihydropyrroles were produced in a facile manner in good yields (up to 90%).