1437682-43-3

Basic information

• Product Name: benzyl (2S,5R)-(-)-5-allyl-2-butyrylpyrrolidine-1-carboxylate
• Synonyms: benzyl (2S,5R)-(-)-5-allyl-2-butyrylpyrrolidine-1-carboxylate
• CAS NO: 1437682-43-3
• Molecular Weight: 315.412
• Mol File: 1437682-43-3.mol

Chemical Properties

• CAS DataBase Reference: benzyl (2S,5R)-(-)-5-allyl-2-butyrylpyrrolidine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl (2S,5R)-(-)-5-allyl-2-butyrylpyrrolidine-1-carboxylate(1437682-43-3)
• EPA Substance Registry System: benzyl (2S,5R)-(-)-5-allyl-2-butyrylpyrrolidine-1-carboxylate(1437682-43-3)

Safety Data

• Hazardous Substances Data: 1437682-43-3(Hazardous Substances Data)

Downstream Products

• 1437682-52-4 benzyl (2S,2αS,5R)-(+)-2-(1-hydroxybutyl)-5-[(E)-4-oxohept-2-enyl]pyrrolidine-1-carboxylate 
• 1437682-55-7 benzyl (2S,2αS,5R)-2-(1-hydroxybutyl)-5-[(E)-4-oxoundec-2-enyl]-pyrrolidine-1-carboxylate 
• 1437682-39-7 benzyl (2S,2αS,5R)-(-)-5-allyl-2-(1-hydroxybutyl)pyrrolidine-1-carboxylate 
• 1437682-41-1 benzyl (2S,2αR,5R)-(-)-5-allyl-2-(1-hydroxybutyl)pyrrolidine-1-carboxylate 
• 1437682-49-9 benzyl (2S,2αR,5R)-(+)-2-(1-hydroxybutyl)-5-[(E)-4-oxohept-2-enyl]pyrrolidine-1-carboxylate 

Relevant articles and documents

Synthesis and biological activities of the 3,5-disubstituted indolizidine poison frog alkaloid 239Q and its congeners

The first total synthesis of the 3,5-disubstituted indolizidine toad alkaloid 239Q from the known pyrrolidine 1 has been achieved, in seven steps with a 35 % overall yield. The relative stereochemistry of natural 239Q was determined unambiguously by comparison of GC-FTIR spectra of synthetic material with the skin extracts of the toad Melanophryniscus cupreuscapularis. The C7 congeners at the 5-position (12 and 13) showed strong antagonist activities on the α4β2 nicotinic acetylcholine receptors.