143770-55-2Relevant academic research and scientific papers
Preparation of Benzonaphthyridines
Nutaitis, Charles F.,Marsh, Stephen R.
, p. 971 - 973 (2007/10/02)
A divergent synthesis of substituted benzonaphthryridines 5a-h is described, which features an intramolecular pyridine cyclization step as the key reaction.The pyridine precursors are conveniently prepared from the pyridinium hydrochloride 2 and the requisite anilines.Cyclization of the non-symmetric substrates 3e and 3f did not proceed with significant regioselectivity.
