1437775-78-4

Basic information

• Product Name: 2-methoxy-N'-(3-pyridinylmethylene)benzohydrazide
• Synonyms: 2-methoxy-N'-(3-pyridinylmethylene)benzohydrazide
• CAS NO: 1437775-78-4
• Molecular Formula: C14H13N3O2
• Molecular Weight: 255.27192
• Mol File: 1437775-78-4.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-methoxy-N'-(3-pyridinylmethylene)benzohydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methoxy-N'-(3-pyridinylmethylene)benzohydrazide(1437775-78-4)
• EPA Substance Registry System: 2-methoxy-N'-(3-pyridinylmethylene)benzohydrazide(1437775-78-4)

Safety Data

• Hazardous Substances Data: 1437775-78-4(Hazardous Substances Data)

Upstream product

• 606-45-1 2-methoxybenzoic acid methyl ester 
• 500-22-1 3-pyridinecarboxaldehyde 
• 7466-54-8 2-methoxybenzoylhydrazine 

Relevant articles and documents

Synthesis of 2-methoxybenzoylhydrazone and evaluation of their antileishmanial activity

Compounds 1-25 showed varying degree of antileishmanial activities with IC50 values ranging between 1.95 and 88.56 μM. Compounds 2, 10, and 11 (IC50 = 3.29 ± 0.07 μM, 1.95 ± 0.04 μM, and 2.49 ± 0.03 μM, respectively) were found to be more active than standard pentamidine (IC50 = 5.09 ± 0.04 μM). Compounds 7 (IC50 = 7.64 ± 0.1 μM), 8 (IC50 = 13.17 ± 0.46 μM), 18 (IC50 = 13.15 ± 0.02 μM), and 24 (IC 50 = 15.65 ± 0.41 μM) exhibited good activities. Compounds 1, 3, 4, 5, 9, 12, 15, 18, and 19 were found to be moderately active. Compounds 13, 14, 16, 17, 20-25 showed weak activities with IC50 values ranging between 57 and 88 μM.