143794-08-5

Upstream product

• 63923-58-0 (R)-(+)-cyanomethyl p-tolyl sulfoxide 
• 142835-85-6 (1R,2R,αR,Rs)-(+)-5,5-dimethyl-2-isopropenyl-α-p-toluenesulfinylcyclohexaneacetonitrile 
• 142835-91-4 (1R,2S,αR,Rs)-(+)-5,5-dimethyl-2-isopropyl-α-p-toluenesulfinylcyclohexaneacetonitrile 
• 17920-90-0 3,3,7-trimethyl-oct-6-enal 
• 142835-92-5 (S)-(-)-5,5-dimethyl-2-isopropylcyclohexylideneacetonitrile 
• 142835-84-5 (S)-(+)-5,5,9-trimethyl-2-p-toluenesulfinyl-2,8-decadienonitrile 

Downstream Products

• 142835-90-3 (S)-(-)-4,4-dimethyl-1-isopropyl-2-methylidenecyclohexane 

Relevant academic research and scientific papers

The Lewis acid-catalyzed intramolecular asymmetric ene reaction using a chiral α-cyanovinylic sulfoxide as an enophile

A chiral α-cyanovinylic sulfoxide served as an efficient chiral enophile in a Lewis acid-catalyzed intramolecular ene reaction. Use of diethylaluminum chloride as a catalyst provided extremely high stereoselectivity in the ene reaction. The stereochemistry of the ene reaction products were determined by chemical correlation and the NMR spectral analysis. A mechanistic pathway for the asymmetric induction is presented on the basis of the stereochemical results obtained.

Lewis Acid-catalyzed Intramolecular Asymmetric Ene Reactions of Chiral Vinyl Sulfoxides

A chiral α-cyanovinyl sulfoxide served as an efficient chiral enophile in a Lewis acid-catalyzed intramolecular ene reaction.Use of diethylaluminum chloride as a catalyst provided extremely high stereoselectivity in this ene reaction.Based on the stereochemical results obtained, a mechanistic pathway for this asymmetric induction is presented.