1438251-51-4

Basic information

• Product Name: 2-chlorophenyl 2-methoxy-3-pyridyl ketone
• Synonyms: 2-chlorophenyl 2-methoxy-3-pyridyl ketone
• CAS NO: 1438251-51-4
• Molecular Weight: 247.681
• Mol File: 1438251-51-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-chlorophenyl 2-methoxy-3-pyridyl ketone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chlorophenyl 2-methoxy-3-pyridyl ketone(1438251-51-4)
• EPA Substance Registry System: 2-chlorophenyl 2-methoxy-3-pyridyl ketone(1438251-51-4)

Safety Data

• Hazardous Substances Data: 1438251-51-4(Hazardous Substances Data)

Upstream product

• 1628-89-3 2-methoxypyridine 
• 609-65-4 o-chlorobenzoyl chloride 

Downstream Products

• 1246461-87-9 (2-methoxypyridin-3-yl)(phenyl)methanone 
• 6537-46-8 5H-benzopyrano[2,3-b]pyridin-5-one 

Relevant articles and documents

Efficient two-step access to azafluorenones and related compounds

Crystals of a lithiocuprate prepared from copper(I) chloride and lithium 2,2,6,6-tetramethylpiperidide (2 equiv) were isolated and analyzed by X-ray diffraction as (TMP)2Cu(Cl)Li2·THF. The observation of this species is consistent with its having a role in deprotocupration- aroylation. Phenyl pyridyl ketones, phenyl quinolyl ketones, and phenyl thienyl ketones were prepared in tetrahydrofuran using the lithiocuprate and aroyl chorides as electrophiles. Diaryl ketones bearing a chloro group at the 2 position (of a pyridyl or phenyl group) thus synthesized were next converted through palladium-catalyzed ring closure to polycycles of the 5H-indeno[1,2-b]pyridin-5-one, 11H-indeno[1,2-b]quinolin-11-one, 9H-indeno[2,1-c]pyridin-9-one, and 8H-indeno[2,1-b]thiophen-8-one families.