1438280-00-2

Upstream product

• 10285-80-0 N-tosyl-3-butenylamine 
• 166319-26-2 1-(propa-1,2-dien-1-yloxy)pentane 

Downstream Products

• 1438279-63-0 (S)-6-(pentyloxy)-1-tosyl-1,2,3,6-tetrahydropyridine 
• 1438279-74-3 (2S,3R,4R)-2-(pentyloxy)-1-tosylpiperidine-3,4-diol 
• 1438279-82-3 (1R,2S,6R)-2-(pentyloxy)-3-tosyl-7-oxa-3-azabicyclo[4.1.0]heptane 
• 1438279-93-6 (1S,2S,6S)-2-(pentyloxy)-3-tosyl-7-oxa-3-azabicyclo[4.1.0]heptane 
• 1438279-88-9 (2S,3R,4R)-3,4-bis(tert-butyldimethylsilyloxy)-2-(pentyloxy)-1-tosylpiperidine 
• 1438279-89-0 (2R,3S,4R)-3,4-bis(tert-butyldimethylsilyloxy)-2-(prop-2-ynyl)-1-tosylpyrrolidine 
• 1438279-98-1 (2S,3S,4R)-3,4-bis(tert-butyldimethylsilyloxy)-2-(prop-2-ynyl)-1-tosylpyrrolidine 
• 1438279-90-3 (2R,3S,4R)-3,4-bis(tert-butyldimethylsilyloxy)-2-(prop-2-ynyl)-1-tosylpiperidine 
• 1438280-08-0 (2S,3S,4R)-3,4-bis(tert-butyldimethylsilyloxy)-2-(prop-2-ynyl)-1-tosylpiperidine 
• 1438279-91-4 (2R,3S,4R)-3,4-bis((tert-butyldimethylsilyl)oxy)-1-tosylpiperidine-2-carbonitrile 
• 1438279-99-2 (2S,3S,4R)-3,4-bis((tert-butyldimethylsilyl)oxy)-1-tosylpiperidine-2-carbonitrile 

Relevant academic research and scientific papers

Access to trans-3,4-Dihydroxy-2-alkylpyrrolidines and piperidines by use of stereodefined cyclic N,O-Acetals as a Diversity-generating element

A highly efficient and stereoselective synthetic pathway towards trans-3,4-dihydroxy-2-alkylpyrrolidines and piperidines is described. The nature of the protecting groups on the hydroxyl moieties played a crucial role on the trans selectivity. By using this method, a concise total synthesis of (-)-2-epilentiginosine has been achieved.

Synthetic strategy for cyclic amines: A stereodefined cyclic N,O-acetal as a stereocontrol and diversity-generating element

In control: A new synthetic strategy towards cyclic amines was developed and exploits a stereodefined cyclic N,O-acetal as the key stereocontrol and diversity-generating element. The cyclic N,O-acetal was prepared from the sequential asymmetric hydroamina