1438286-68-0

Basic information

• Product Name: 2-(1-(4-methoxyphenyl)vinyl)-6-(1H-pyrazol-1-yl)pyridine
• Synonyms: 2-(1-(4-methoxyphenyl)vinyl)-6-(1H-pyrazol-1-yl)pyridine
• CAS NO: 1438286-68-0
• Molecular Weight: 277.326
• Mol File: 1438286-68-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(1-(4-methoxyphenyl)vinyl)-6-(1H-pyrazol-1-yl)pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(1-(4-methoxyphenyl)vinyl)-6-(1H-pyrazol-1-yl)pyridine(1438286-68-0)
• EPA Substance Registry System: 2-(1-(4-methoxyphenyl)vinyl)-6-(1H-pyrazol-1-yl)pyridine(1438286-68-0)

Safety Data

• Hazardous Substances Data: 1438286-68-0(Hazardous Substances Data)

Upstream product

• 32117-52-5 1-(1-(4-methoxyphenyl)ethylidene)-2-tosylhydrazine 
• 123640-41-5 2-bromo-6-(1H-pyrazol-1-yl)pyridine 
• 100-06-1 1-(4-methoxyphenyl)ethanone 

Relevant articles and documents

An efficient coupling of N-tosylhydrazones with 2-halopyridines: Synthesis of 2-α-styrylpyridines endowed with antitumor activity

The synthesis of 2-α-styrylpyridines has been carried out by using the coupling of polyoxygenated N-tosylhydrazones with various 2-halopyridines. We demonstrated that the use of a catalytic amount of PdCl2(MeCN) 2 in combination with a bidentate ferrocene DPPF or a monodentate alkyl phosphine tBu2MeP-HBF4 constitutes an efficient protocol for this coupling, providing 2-α-styrylpyridines 2 in satisfactory to good yields. Among several polyoxygenated derivatives 2 evaluated, compound 2aa was found to exhibit excellent antiproliferative and antimitotic activities comparable to that of the reference compound isoCA-4. The Royal Society of Chemistry 2013.