1438287-41-2Relevant academic research and scientific papers
A novel domino strategy for forming poly-substituted quaternary imidazoles through a Cs2CO3-promoted aryl migration process
Xu, Hai-Wei,Fan, Wei,Li, Meng-Yuan,Jiang, Bo,Wang, Shu-Liang,Tu, Shu-Jiang
supporting information, p. 3603 - 3607 (2013/06/26)
A new domino strategy for the synthesis of highly functionalized quaternary imidazole derivatives via [3 + 2] heterocyclization, involving aryl migration and ring-opening of oxirane, has been developed. This domino reaction enables the successful assembly of three new sigma bonds including two C-N bonds in a simple operation. Features of this strategy include the mild conditions, convenient operation, and short reaction periods (15-20 min). The Royal Society of Chemistry 2013.
