14383-43-8 Usage
General Description
(2,6-DIOXO-3,6-DIHYDROPYRIMIDIN-1(2H)-YL)ACETIC ACID is a chemical compound with the molecular formula C6H6N2O4. It is a derivative of pyrimidine and is used in the synthesis of various pharmaceuticals and agrochemicals. The compound has been studied for its potential use in the treatment of various diseases, including cancer and infectious diseases. It has also been used as a building block in the synthesis of nucleotide analogs and other bioactive compounds. Overall, (2,6-DIOXO-3,6-DIHYDROPYRIMIDIN-1(2H)-YL)ACETIC ACID plays an important role in the development of new drugs and chemical compounds with potential medicinal and agricultural applications.
Check Digit Verification of cas no
The CAS Registry Mumber 14383-43-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,3,8 and 3 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 14383-43:
(7*1)+(6*4)+(5*3)+(4*8)+(3*3)+(2*4)+(1*3)=98
98 % 10 = 8
So 14383-43-8 is a valid CAS Registry Number.
InChI:InChI=1/C6H6N2O4/c9-4-1-2-7-6(12)8(4)3-5(10)11/h1-2H,3H2,(H,7,12)(H,10,11)
14383-43-8Relevant articles and documents
ALKYLATION OF 2-METHYLTHIO-4-HYDROXYPYRIMIDINES BY METHYL BROMOACETATE
Vainilavichyus, P. I.,Syadyaryavichyute, V. Yu.
, p. 1216 - 1218 (1987)
2-Methylthio-4-hydroxypyrimidines react with methylbromoacetate in methanol-sodium methoxide solution to give O- and N(3)-alkylated products, namely, 2-methylthio-4-(methoxycarbonyl)methoxypyrimidines and 2-methylthio-3-(methoxycarbonyl)methylpyrimid-4-ones.
SYNTHESIS OF REGIOSPECIFICALLY SUBSTITUTED PYRIMIDYL DERIVATIVES AND THEIR INCORPORATION INTO PENEMS
Capraro, Hans-Georg,Lang, Marc,Schneider, Peter
, p. 643 - 652 (2007/10/02)
Syntheses of regiospecifically substituted pyrimidines are described.Depending on the reaction conditions, N1- or N3-substituted pyrimidines are obtained.It has been shown that substitution on uracil under Mitsunobu conditions yields N1-substituted products.Incorporation of these derivatives into the penem nucleus gives penem antibiotics with extremely long half-lives.